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24 result(s) for 'author#Alvis Brazma' within BMC

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  6. RNA sequencing has opened new avenues for the study of transcriptome composition. Significant evidence has accumulated showing that the human transcriptome contains in excess of a hundred thousand different tr...

    Authors: Mar Gonzàlez-Porta, Adam Frankish, Johan Rung, Jennifer Harrow and Alvis Brazma
    Citation: Genome Biology 2013 14:R70
    Content type: Research Published on:

  7. One of the crucial aspects of day-to-day laboratory information management is collection, storage and retrieval of information about research subjects and biomedical samples. An efficient link between sample d...

    Authors: Juris Viksna, Edgars Celms, Martins Opmanis, Karlis Podnieks, Peteris Rucevskis, Andris Zarins, Amy Barrett, Sudeshna Guha Neogi, Maria Krestyaninova, Mark I McCarthy, Alvis Brazma and Ugis Sarkans
    Citation: BMC Bioinformatics 2007 8:52
    Content type: Software Published on:

  8. Recent studies in comparative genomics demonstrate that interspecies comparison represents a powerful tool for identifying both conserved and specialized biologic processes across large evolutionary distances....

    Authors: Gabriella Rustici, Harm van Bakel, Daniel H Lackner, Frank C Holstege, Cisca Wijmenga, Jürg Bähler and Alvis Brazma
    Citation: Genome Biology 2007 8:R73
    Content type: Research Published on:

  10. Sharing of microarray data within the research community has been greatly facilitated by the development of the disclosure and communication standards MIAME and MAGE-ML by the MGED Society. However, the comple...

    Authors: Tim F Rayner, Philippe Rocca-Serra, Paul T Spellman, Helen C Causton, Anna Farne, Ele Holloway, Rafael A Irizarry, Junmin Liu, Donald S Maier, Michael Miller, Kjell Petersen, John Quackenbush, Gavin Sherlock, Christian J Stoeckert Jr, Joseph White, Patricia L Whetzel…
    Citation: BMC Bioinformatics 2006 7:489
    Content type: Commentary Published on:

  11. Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations are limiting factors,...

    Authors: Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Matthias W Hentze, Thomas Dandekar and Martina U Muckenthaler
    Citation: BMC Bioinformatics 2010 11:112
    Content type: Software Published on:

  12. With genome analysis expanding from the study of genes to the study of gene regulation, 'regulatory genomics' utilizes sequence information, evolution and functional genomics measurements to unravel how regula...

    Authors: Martin Vingron, Alvis Brazma, Richard Coulson, Jacques van Helden, Thomas Manke, Kimmo Palin, Olivier Sand and Esko Ukkonen
    Citation: Genome Biology 2009 10:202
    Content type: Review Published on:

  13. Genes for the production of a broad range of fungal secondary metabolites are frequently colinear. The prevalence of such gene clusters was systematically examined across the genome of the cereal pathogen Fusariu...

    Authors: Katherine Lawler, Kim Hammond-Kosack, Alvis Brazma and Richard MR Coulson
    Citation: BMC Systems Biology 2013 7:52
    Content type: Research article Published on:

  16. Gene regulatory networks can be modelled in various ways depending on the level of detail required and biological questions addressed. One of the earliest formalisms used for modeling is a Boolean network, alt...

    Authors: Dace Ruklisa, Alvis Brazma, Karlis Cerans, Thomas Schlitt and Juris Viksna
    Citation: BMC Bioinformatics 2019 20:296
    Content type: Research article Published on:

  17. A vast amount of DNA variation is being identified by increasingly large-scale exome and genome sequencing projects. To be useful, variants require accurate functional annotation and a wide range of tools are ...

    Authors: Adam Frankish, Barbara Uszczynska, Graham RS Ritchie, Jose M Gonzalez, Dmitri Pervouchine, Robert Petryszak, Jonathan M Mudge, Nuno Fonseca, Alvis Brazma, Roderic Guigo and Jennifer Harrow
    Citation: BMC Genomics 2015 16(Suppl 8):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 16 Supplement 8

  18. Although high-throughput studies of gene expression have generated large amounts of data, most of which is freely available in public archives, the use of this valuable resource is limited by computational com...

    Authors: Jing Su, Carl Ekman, Nikolay Oskolkov, Leo Lahti, Kristoffer Ström, Alvis Brazma, Leif Groop, Johan Rung and Ola Hansson
    Citation: Skeletal Muscle 2015 5:35
    Content type: Research Published on:

  19. Translational researchers need robust IT solutions to access a range of data types, varying from public data sets to pseudonymised patient information with restricted access, provided on a case by case basis. ...

    Authors: Marco Brandizi, Olga Melnichuk, Raffael Bild, Florian Kohlmayer, Benedicto Rodriguez-Castro, Helmut Spengler, Klaus A. Kuhn, Wolfgang Kuchinke, Christian Ohmann, Timo Mustonen, Mikael Linden, Tommi Nyrönen, Ilkka Lappalainen, Alvis Brazma and Ugis Sarkans
    Citation: BMC Medical Informatics and Decision Making 2017 17:30
    Content type: Technical advance Published on: