|
Test results of the 18 parameters implemented in miRFinder |
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| Parameters |
Pre-miRNA |
Non-miRNA Hairpins |
Parameter Test |
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|
|
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| ID |
Symbol |
Mean |
Std. Deviation |
Mean |
Std. Deviation |
F value |
T test |
|
|
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| 01 |
pMFE |
-0.444 |
0.072 |
-0.218 |
0.086 |
1.44 |
0.000 |
| 02 |
pVMFE |
0.455 |
0.936 |
0.506 |
0.632 |
0.03 |
0.014 |
| 03 |
pVStrc |
0.903 |
1.812 |
3.635 |
4.703 |
0.41 |
0.000 |
| 04 |
pMatch |
0.892 |
0.063 |
0.639 |
0.176 |
1.06 |
0.000 |
| 05 |
pDI |
0.050 |
0.058 |
0.088 |
0.126 |
0.21 |
0.000 |
| 06 |
pMismatch |
0.097 |
0.060 |
0.196 |
0.119 |
0.55 |
0.000 |
| 07 |
pBulge |
0.014 |
0.036 |
0.169 |
0.209 |
0.64 |
0.000 |
| 08 |
pMutFreq |
0.018 |
0.024 |
0.136 |
0.126 |
0.78 |
0.000 |
| 09 |
"=-" |
0.043 |
0.029 |
0.035 |
0.031 |
0.13 |
0.000 |
| 10 |
"==" |
0.649 |
0.081 |
0.466 |
0.089 |
1.08 |
0.000 |
| 11 |
"=:" |
0.090 |
0.041 |
0.093 |
0.037 |
0.04 |
0.001 |
| 12 |
"--" |
0.023 |
0.041 |
0.043 |
0.076 |
0.17 |
0.000 |
| 13 |
"-=" |
0.043 |
0.029 |
0.035 |
0.031 |
0.13 |
0.000 |
| 14 |
"^^" |
0.008 |
0.021 |
0.090 |
0.130 |
0.54 |
0.000 |
| 15 |
"^=" |
0.014 |
0.018 |
0.044 |
0.026 |
0.69 |
0.000 |
| 16 |
"::" |
0.044 |
0.044 |
0.102 |
0.086 |
0.45 |
0.000 |
| 17 |
":^" |
0.014 |
0.018 |
0.044 |
0.026 |
0.69 |
0.000 |
| 18 |
":=" |
0.076 |
0.041 |
0.048 |
0.037 |
0.36 |
0.000 |
|
Note: T tests are 2-tailed. The F value represents the discriminative power of the parameters. The 18 parameters were coded as. 1: Minimum Free Energy; 2: The difference of the MFE of the sequence pair; 3: The difference of the structure of the sequence pair; 4–7: Base pairing and other properties of the 22 mer hypothesized mature miRNA; 8: The mutation frequency of the sequence segment pair; 9–18: The frequency of the 10 possible secondary structure elements (combinations of 2 adjacent characters) in the pseudo code of stem region (represented by the new syntax). [See details in additional file 1]. | |||||||
Huang et al. BMC Bioinformatics 2007 8:341 doi:10.1186/1471-2105-8-341 |
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