|
Unique features of human PPI databases |
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| Number of unique human PPIs |
Number of proteins |
PPI data |
Unique features |
Download options |
PSI-MI compatibility |
Download version number |
|
|
|
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| HPRD |
36,617 |
9,427 |
Experimental |
Protein annotations are included (e.g. PTMs, substrate information, tissue expression, disease association, protein complexes, subcellular localization). Signal transduction pathways |
Yes |
Yes |
Release 6 |
| BIND |
6,621 |
3,887 |
Experimental |
Protein complexes, biological pathways, non-protein interactions, Data for >1473 organisms |
Yes |
Yes |
20060525 |
| DIP |
1,067 |
804 |
Experimental |
PPIs for other organisms, protein complexes |
Yes |
Yes |
Hsapi20060402 |
| MINT |
11,367 |
4,975 |
Experimental |
PPIs for other organisms, non-protein interactions |
Yes |
Yes |
Version 18 |
| PDZBase |
101 |
115 |
Experimental |
PPIs involving PDZ domains. Prediction of residues that interact. |
No |
No |
October 2, 2006 |
| MIPS |
346 |
405 |
Experimental |
PPIs for other organisms |
Yes |
Yes |
October 2, 2006 |
| IntAct |
10,244 |
4,614 |
Experimental |
Protein complexes, PPIs for other organisms, non-protein interactions, provides web based applications, ProViz and Hierarch View, for visualization of interactions |
Yes |
Yes |
2006-09-22 |
| AfCS |
Mostly mouse interactions |
Mostly mouse proteins |
Experimental |
Protein annotations are included (e.g. function, subcellular localization, orthologs, tissue expression, mouse knockout phenotype information, PTMs) |
No |
No |
- |
| REACTOME |
5,960 |
970 |
Experimental, automated and predicted |
Biological pathways for several organisms. Navigation through reactions in biological pathways and visualizing connections between them |
Yes |
No |
Version 18 |
Mathivanan et al. BMC Bioinformatics 2006 7(Suppl 5):S19 doi:10.1186/1471-2105-7-S5-S19 |
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