Table 3

SVM prediction of caspase substrate cleavage sites in Livin and mutants.

Substrate^a

Experimental Results^b

SVM Prediction^c

Wild type Livin

Cleaved

Cleaved

LE Δ52–61

Not cleaved

Cleaved

Δ53–55

Cleaved

Cleaved

Δ55–57

Cleaved

Cleaved

Δ57–59

Cleaved

Cleaved

Δ60–62

Cleaved

Cleaved

Δ52–61

Not cleaved

Not cleaved

Δ53–61

Not cleaved

Cleaved

Δ52

Not cleaved

Not cleaved

Δ51–53

Not cleaved

Cleaved

a. Wild type Livin and various deletion mutants as reported in Yan et al. b Experimentally verified cleavage (cleaved) or non-cleavage (not cleaved) of Livin and deletion mutants. c. SVM prediction of caspase cleavage sites on Livin and deletion mutants (Cleaved – presence of cleavage site; Not cleaved -absence of cleavage site).

Wee et al. BMC Bioinformatics 2006 7(Suppl 5):S14   doi:10.1186/1471-2105-7-S5-S14