Table 1

The sequences with the top ten "most informatively" predicted correct annotations by the aggregate algorithm are summarized.

Sequence

Gene symbol

Gold standard

Closest informative prediction

Pre-existing IEA terms (representative)

Pub Date


BHMT1_MOUSE

Bhmt

methionine biosynthetic process (GO:0009086)

methionine biosynthetic process (GO:0009086)

methionine biosynthetic process

2004


IPO13_RAT

Ipo13

steroid hormone receptor nuclear translocation (GO:0002146)

protein import into nucleus, translocation (GO:0000060)

protein import into nucleus

2006


ARGB_ECOLI

argb

arginine biosynthetic process (GO:0006526)

arginine biosynthetic process (GO:0006526)

arginine biosynthetic process

2007


CAF1K_ARATH

CAF1-11

nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)

nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)

poly(A)-specific ribonuclease activity

2009


CFAB_MOUSE

Cfb

complement activation, alternative pathway (GO:0006957)

complement activation, alternative pathway (GO:0006957)

complement activation

1983


CHM4B_HUMAN

CHMP4B

endosome transport (GO:0016197)

endosome transport (GO:0016197)

protein transport; late endosome membrane

2010 (Reactome)


HA15_MOUSE

H2-T23

antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway (GO:0002488)

antigen processing and presentation of endogenous peptide antigen via MHC class Ib (GO:0002476)

antigen processing and presentation of peptide antigen via MHC class I

1992


SOX11_MOUSE

Sox11

positive regulation of hippo signaling pathway (GO:0035332)

embryonic digestive tract morphogenesis (GO:0048557)

cell differentiation;nervous system development

2010


TGT_ECOLI

tgt

tRNA wobble guanine modification (GO:0002099)

queuosine metabolic process (GO:0046116)

queuine tRNA-ribosyltransferase activity

1982


VATL_MOUSE

Atp6v0c

lysosomal lumen acidification (GO:0007042)

lysosomal lumen acidification (GO:0007042)

proton-transporting V-type ATPase, V0 domain;vacuole

2001


The date of publication of the gold standard source is given in the last column.

Gillis and Pavlidis BMC Bioinformatics 2013 14(Suppl 3):S15   doi:10.1186/1471-2105-14-S3-S15

Open Data