Example of predicted functional residues. Residues predicted by the method as associated to the GO:0004672 ("protein kinase activity") function for the casein kinase 1 ([PDB:2csn]A) mapped in the structure of this protein. Red and purple: predicted residues. Blue and purple: catalytic residues annotated in CSA. The prosthetic groups are shown in grey and spacefill. Figure generated with PyMOL (http://www.pymol.org webcite).
Lopez and Pazos BMC Bioinformatics 2013 14(Suppl 3):S12 doi:10.1186/1471-2105-14-S3-S12