Table 2

Results from modRP analysis of cocaine (C), opium (O), nicotine (N), and alcohol (A) dependence comorbidities in Combined, EA, and AA populations.

COMBINED (EA & AA) Population


Four

Three

Two


CO

rs1476880*

3.30E-05


CONA

rs1476880

1.55E-05

CON

rs1476880*

2.26E-06

CN

rs1476880*

5.30E-06

SOD3


CONA

rs1426165

2.68E-03

CNA

rs1426165

6.87E-04

CN

rs1426165

2.97E-04

ADAMTSL3


CONA

rs1169791*

1.23E-05

CNA

rs1925156*

1.20E-05

CA

rs1938584*

3.07E-05


COA

rs1938584*

3.35E-05

ON

rs1860148*

5.61E-05


ONA

rs1385513*

1.07E-04

OA

rs726427*

3.66E-04


NA

rs2169325*

1.57E-04


EUROPEAN AMERICANS


Four

Three

Two


CO

rs1476880

3.32E-05


CONA

rs1476880

1.59E-05

CON

rs1476880*

2.23E-06

CN

rs1476880*

5.38E-06

SOD3


CONA

rs1426165

2.67E-03

CNA

rs1426165

6.87E-04

CN

rs1426165

2.97E-04

ADAMTSL3


CONA

rs1169791*

1.26E-05

CNA

rs1925156*

1.20E-05

CA

rs1938584*

3.06E-05


COA

rs1938584*

3.33E-05

ON

rs1860148*

5.61E-05


ONA

rs1385513*

1.07E-04

OA

rs726427*

3.66E-04


NA

rs2169325*

1.57E-04


AFRICAN AMERICANS


Four

Three

Two


CON

rs726344*

2.70E-05

CO

rs1015343*

9.50E-05


CONA

rs1476880

2.46E-04

CON

rs1476880

4.47E-05

CN

rs1476880

2.01E-05

SOD3


CONA

rs1426165

7.44E-05

CNA

rs1426165*

1.73E-05

CN

rs1426165*

3.62E-06

ADAMTSL3


COA

rs910633*

8.32E-05

CA

rs763869*

4.54E-05


ON

rs897119*

1.05E-04


CONA

rs795734*

5.03E-05

ONA

rs795734*

9.12E-06

OA

rs795734

7.06E-05


NA

rs795734

1.07E-04


In each population, the 4-way (Four), 3-way (Three), and 2-way (Two) comorbidities proceed from left to right. * Indicates the most significant result for each comorbid phenotype, in each population. For reference, complete results for rs1426165 and rs1476880 are included in each population set. Bonferroni Corrected Threshold: 8.88e-006

McEachin et al. BMC Bioinformatics 2012 13(Suppl 2):S8   doi:10.1186/1471-2105-13-S2-S8

Open Data