Substrate satisfaction condition for applying enzyme reactions. As a constraint for applying a reaction rule to a compound, the substrate inclusion condition is modeled by inclusion of the substrate vector. When attempting to apply the reaction rule R = (U, O) to a compound vector C, the compound vector C must include the substrate vector U as part of its own structure. That is, for any k, the value ck in the compound vector C = (c1, ..., cn) must exceed the value uk in the substrate vector U = (u1, ..., un).
Nakamura et al. BMC Bioinformatics 2012 13(Suppl 17):S8 doi:10.1186/1471-2105-13-S17-S8