Table 1

Predicted Recurrent Breakpoints in 36 Prostate Samples.

Breakpoint Type

Rearrangement Type(s)

# Predicted

# in DGV

# Novel


Recurrent Probes

Highly Conserved Breakpoints

80

66

14


Recurrent Genes

Gene Truncations

6

5

1


Pairs of Recurrent Probes

Germline or Somatic

Structural Variants

38

28

10


Pairs of Recurrent Genes

Intrachromosomal Fusion Genes

2

1

1


With Fusion Gene Config.*

Interchromosomal Fusion Genes

2

2

0


Breakpoint types are described by the indicated rearrangement type. '# Predicted' is the number of predictions that are significant with FDR < 0.01. '# in DGV' counts the breakpoints near known structural variants in the Database of Genomic Variants (DGV). '# Novel' is the number of predictions that are not near any known variant in DGV.

* Novel pairs of recurrent gene breakpoints consistent with the fusion gene configuration.

Ritz et al. BMC Bioinformatics 2011 12:114   doi:10.1186/1471-2105-12-114

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