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Igor Jurisica

  1. Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biological pathways of regulation. Most current a...

    Authors: Hiroko K Solvang, Ole Christian Lingjærde, Arnoldo Frigessi, Anne-Lise Børresen-Dale and Vessela N Kristensen

    Citation: BMC Bioinformatics 2011 12:197

    Content type: Research article

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  2. Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array comparative genome hybridization (aCGH) and next-...

    Authors: Anna Ritz, Pamela L Paris, Michael M Ittmann, Colin Collins and Benjamin J Raphael

    Citation: BMC Bioinformatics 2011 12:114

    Content type: Research article

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  3. Cellular processes and pathways, whose deregulation may contribute to the development of cancers, are often represented as cascades of proteins transmitting a signal from the cell surface to the nucleus. Howev...

    Authors: Enrico Glaab, Anaïs Baudot, Natalio Krasnogor and Alfonso Valencia

    Citation: BMC Bioinformatics 2010 11:597

    Content type: Methodology article

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