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This article is part of the supplement: Selected articles from the Eighth Asia-Pacific Bioinformatics Conference (APBC 2010)

Open Access Research

Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks

MS Vijayabaskar and Saraswathi Vishveshwara*

Author Affiliations

Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India

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BMC Bioinformatics 2010, 11(Suppl 1):S49  doi:10.1186/1471-2105-11-S1-S49

Published: 18 January 2010

Additional files

Additional file 1:

Network parameter comparison of PENs in thermophilic and mesophilic proteins. Figure S1 shows the comparison of the largest connected component as a function of 'e' between the thermophile/mesophile homologs. Similarly, Figure S2, S4, S5 and S6 show such comparison for the cluster population, largest community size, clique population and hub population respectively. Figure S3 shows the comparison of different network parameters between one thermophilic and two mesophilic carboxypeptidases. Table S1 gives an overview of the different network parameters (at a specific 'e') across the whole dataset, along with some commonly analyzed pairwise interactions.

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