The neuronally expressed transcription factor gene ewg is shown to be a major target of the RNA-binding protein ELAV. EWG restricts synaptic growth at neuromuscular junctionsby integrating multiple signal pathways.
Transcript and metabolite abundance changes were analyzed in evolved and ancestor strains of Escherichia coli in three different evolutionary conditions
ModuleMiner detects cis-regulatory modules in a set of co-expressed genes in tissue-specific microarray clusters and in embryonic development datasets.
Novel cofactors of Mash1 and Ngn2, proneural genes involved in mammalian brain development, have been identified by a combination of experimental and bioinformatic approaches, establishing a new understanding of the gene regulatory networks behind neurogenesis.
A comprehensive review of the seven main research areas by 56 experts has identified the key gaps and priorities for the greatest potential impact on breast cancer patients.