Stem Cell Gateway
Welcome to the BioMed Central Stem Cell Gateway, highlighting the latest articles we have published in the stem cell field. Content is continually updated, so please bookmark this page and ensure you check it regularly.
Copolymer scaffolds can be prevascularized with endothelial cells (EC) and mesenchymal stem cells (MSC); seeding of MSC with or without EC increases the osteogenic potential of tissue-engineered constructs.
Adult neural stem cells extracted from the olfactory bulb of diabetic rats can be cultured in vitro and show similar gene expression profiles to hippocampal neural stem cells during diabetes progression.
Human first-trimester decidua side population cells can differentiate into endothelial cells and form tube-like structures in vitro and may induce vasculogenesis in vivo in the ischemic limb nude mouse model.
Induced pluripotent stem cells from the skin of patients with Dravet syndrome show Dravet-like functional impairment when they are converted into neurons, providing an unparalleled insight into the mechanism behind this rare form of infantile-onset epilepsy.
Higher expression levels of the hematopoiesis-related genes SALL4 and BMI-1 in placental tissue compared with umbilical cord blood suggest it might be a good source for expansion of hematopoietic progenitor cells (HPCs).
Intravenous administration of cryopreserved allogeneic adipose-derived mesenchymal stem cells in cats with chronic kidney disease resulted in significant adverse effects and no clinical improvement.
Celia Gomes comments on research showing human mesenchymal stem cells (MSCs) slow tumor growth in established murine tumors, whereas MSC administration appears to increase growth in newly formed tumors.
Injection of human mesenchymal stem cells into established tumors in mice slowed tumor growth, and this effect appeared to be due to changes in tumor angiogenesis.
Members of Genome Biology's Editorial Board select their highlights from the 60 years of genome biology that followed the double helix
Nestor and Noggle review approaches using bioinformatics and gene profiling to standardize pluripotency assays, one of the major hurdles in the development of high-throughput production of human stem cells for regenerative therapies.
News and events
Clinical applications of stem cells
Stem Cell Research & Therapy has published the first articles in a new thematic series on clinical applications of stem cells and is now inviting research submissions for the series. For more information read the introductory editorial from Series Editor Mahendra Rao (National Institutes of Health, USA), or the related blog post.
Cell Regeneration has published its first set of high quality research articles with BioMed Central. It welcomes novel research articles as well as in depth reviews in modern biology, especially in the field of stem cell and regenerative biology, and regenerative medicine. The journal is supported by Guangzhou Institute of Biomedicine and Health, which covers APCs for all authors. In the launch issue it presented novel approaches to grow cells in vitro or ideas that may eventually help us to regenerate cell or tissues in vivo. Read more at the launch blog.
Focus on Stem Cells - a new thematic series
The explosion of interest in stem cells, over the past decade or so, in both basic and translational research has encouraged three of BioMed Central's flagship journals, BMC Biology, BMC Medicine and Genome Medicine, to come together to present a series of specially commissioned comment and review articles on stem cell biology and medicine. In this thematic series we aim to highlight some of the most important and topical issues - including recent advances, controversies and challenges in stem cell research, and of course their clinical implications. To supplement the comment and review, relevant original research articles will be added to the series as they are published.
Stem cell niche
Stem Cell Research & Therapy 2013, 4:47
Stem Cell Research & Therapy 2013, 4:52
BMC Plant Biology 2013, 13:77