Stem Cell Gateway

Welcome to the BioMed Central Stem Cell Gateway, highlighting the latest articles we have published in the stem cell field. Content is continually updated, so please bookmark this page and ensure you check it regularly.

Articles

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Media for osteogenic differentiation

Lower concentrations of dexamethasone and higher concentrations of L-ascorbic acid 2-phosphate should be used for the in vitro osteogenic differentiation of human adipose stem cells.

Stem Cell Research & Therapy 2013, 4:17
Heart regeneration

Milica Radisic and colleagues review the use of engineered surface topology and electrical control in directing the cardiac differentiation of stem cells and the production of engineered heart tissue.

Stem Cell Research & Therapy 2013, 4:14
Stabilizing synthetic mRNA expression

The small molecule BAY-11 suppresses the innate immune response and enhances the expression of synthetic OCT4 mRNA after transfection into adult human skin cells, with multiple potential research and therapeutic applications.

Stem Cell Research & Therapy 2013, 4:15
Using force to build bone

Warren Grayson and colleagues review the use of mechanical forces to enhance osteogenesis in bone tissue engineering, based on knowledge obtained from mechanobiology studies of native bone.

Stem Cell Research & Therapy 2013, 4:10
Cell therapy for acute lung injury

Anti-inflammatory effects of both human and mouse adipose-derived stem cells (ASC) in the lipopolysaccharide-induced acute lung injury (ALI) mouse model suggest ASC may have clinical potential in ALI.

Stem Cell Research & Therapy 2013, 4:13
Stem cells aid stroke recovery

Rats treated intravenously with bone marrow- or adipose-derived mesenchymal stem cells after experimental ischemic stroke showed improvements in brain and nerve repair, and ability to complete behavioural tasks.

Stem Cell Research & Therapy 2013, 4:11
MSC regulation of microglia responses

Mesenchymal stem cells (MSC) interact in a multifaceted manner with microglia, and their capability to adapt and regulate their specific cellular environment demonstrates their potential for immunomodulatory therapy.

Stem Cell Research & Therapy 2013, 4:12
Stochastic transcription kinetics

A new framework for modeling stochastic gene expression in single cells yields insights into the regulatory role of histone modifications

Genome Biology 2013, 14:R7
Vascular tissue engineering

As part of the Physical influences on stem cells series, Serbo and Gerecht discuss the use of biodegradable scaffolds to control vascular network formation and promote angiogenesis in damaged tissue.

Stem Cell Research & Therapy 2013, 4:8
Digital enigmas

A Research Highlight on the mystery of finger formation: how Alan Turing's proposed reaction-diffusion mechanism underlies digit development

Genome Biology 2013, 14:101

News and events

Clinical applications of stem cells

Stem Cell Research & Therapy has published the first articles in a new thematic series on clinical applications of stem cells and is now inviting research submissions for the series. For more information read the introductory editorial from Series Editor Mahendra Rao (National Institutes of Health, USA), or the related blog post.

Cell Regeneration welcomes your best research

Cell Regeneration has published its first set of high quality research articles with BioMed Central. It welcomes novel research articles as well as in depth reviews in modern biology, especially in the field of stem cell and regenerative biology, and regenerative medicine. The journal is supported by Guangzhou Institute of Biomedicine and Health, which covers APCs for all authors. In the launch issue it presented novel approaches to grow cells in vitro or ideas that may eventually help us to regenerate cell or tissues in vivo. Read more at the launch blog.

Focus on Stem Cells - a new thematic series

The explosion of interest in stem cells, over the past decade or so, in both basic and translational research has encouraged three of BioMed Central's flagship journals, BMC Biology, BMC Medicine and Genome Medicine, to come together to present a series of specially commissioned comment and review articles on stem cell biology and medicine. In this thematic series we aim to highlight some of the most important and topical issues - including recent advances, controversies and challenges in stem cell research, and of course their clinical implications. To supplement the comment and review, relevant original research articles will be added to the series as they are published.