Stem Cell Gateway
Welcome to the BioMed Central Stem Cell Gateway, highlighting the latest articles we have published in the stem cell field. Content is continually updated, so please bookmark this page and ensure you check it regularly.
Anna Köferle, Stefan Stricker, and Stephan Beck discuss targeted epigenome engineering, and the brave new world that has such technologies in't.
miRNA expression profiles of distinct epithelial subpopulations and comparison to gene expression and epigenetic information shed light on the role of miRNA and the epigenome in mammary cell differentiation and oncogenesis.
A new algorithm detects circular RNAs with high sensitivity and specificity and discovers human fetal brain regions enriched for circular RNA isoforms
Single-cell RNA sequencing data provide a unique view of transcriptome function
Wen Xue and colleagues review the recent progress in using genome editing techniques, particularly CRISPR-Cas9, to efficiently develop mouse models of cancer and leukemia.
DNMT1-dependent and –independent methylation patterns play distinct roles in mouse embryonic stem cell genome stability and transcriptional regulation
Roles for ZFP57-mediated regulation of genomic imprinting and a novel mechanism for genetically determined mono-allelic gene expression.
An immunohistochemical study demonstrates that podocalyxin-like protein expression is associated with more aggressive tumor phenotype and poor prognosis in pancreatic, distal bile duct, ampullary and duodenal adenocarcinoma.
Bill Skarnes from Sanger Institute answers a burning question: Is mouse embryonic stem cell technology obsolete?
A robust method for cellular phenotyping in primary human mesenchymal stem cells using kinome fingerprinting to identify gene networks that characterize distinct primary cell populations.
News and events
Stem Cell Research & Therapy has issued a call for research submissions for inclusion in a thematic series on cardiovascular regeneration, edited by Ronald Li.
The series will review the current state-of-the-art stem cell-based approaches for disease modelling, drug discovery and myocardial repair, as well as the associated hurdles and potential solutions. Authors of commissioned reviews include Kenneth Boheler (National Institutes of Health, USA), Steve Oh (BTI, Singapore) and Sean Wu (Stanford University).
Manuscripts should be submitted online, please indicate in the covering letter that they should be considered for the cardiovascular regeneration series. Any enquiries should be directed to the Stem Cell Research & Therapy editorial office.
Regenerative Medicine Research is a new journal that welcomes submissions relating to both the fundamental and practical aspects of regenerative medicine, with a particular emphasis on translational research.
Edited by Y. James Kang, the journal encourages papers from both basic and applied sciences, including the large field of biomedical research in which chronic diseases have become an increasingly prominent area of research, and regenerative medicine has become the first answer of choice.
Stem cell niche
Stem Cell Research & Therapy 2015, 6:128
World Journal of Emergency Surgery 2015, 10:30
BMC Genetics 2015, 16:77