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BMC Research highlights

Genome Biology 2008, 9:R73
The neuronally expressed transcription factor gene ewg is shown to be a major target of the RNA-binding protein ELAV. EWG restricts synaptic growth at neuromuscular junctionsby integrating multiple signal pathways.

Taken from Fig 2C, Lagido et al. 2008
BMC Physiology 2008, 8:7
The metabolism of C. elegans can be assessed in real time by the constitutive expression of firefly luciferase, which reports in vivo levels of ATP.

Breast Cancer Research 2008, 10:R28
Transcript profiling identified an estrogen-responsive target for the mammary oncogene c-Myc, HSPC111, which is overexpressed in breast cancer cells and is associated with adverse patient outcome.

Breast Cancer Research 2008, 10:R26
A comprehensive review of the seven main research areas by 56 experts has identified the key gaps and priorities for the greatest potential impact on breast cancer patients.

Genome Biology 2008, 9:R53
Detailed analysis of NFB regulons in 1,265 genes differentially expressed in head and neck cancer cell lines differing in p53 status revealed a cross talk between NFkB and specific signaling pathways.


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BMC Author profile

Liqun Lu
National University of Singapore


BMC Latest research articles

Research article
Expansion of signaling genes for adaptive immune system evolution in early vertebrates
Kinya Okada, Kiyoshi Asai
BMC Genomics 2008, 9:218 (14May2008)
[Abstract] [Provisional PDF]

Short report
Refined study of the interaction between HIV-1 p6 late domain and ALIX
Carine Lazert, Nathalie Chazal, Laurence Briant, Denis Gerlier, Jean-Claude Cortay
Retrovirology 2008, 5:39 (13May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: comparison of single base mismatches and base bulges
Thomas Naiser, Oliver Ehler, Jona Kayser, Timo Mai, Wolfgang Michel, Albrecht Ott
BMC Biotechnology 2008, 8:48 (13May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
Purna Mukherjee, Tiernan J. Mulrooney, Jeremy Marsh, Derek Blair, Thomas C. Chiles, Thomas N. Seyfried
Molecular Cancer 2008, 7:37 (12May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis
Kyle Hubbard, Jennifer Catalano, Raj K Puri, Averell Gnatt
BMC Cancer 2008, 8:133 (12May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Genomic and bioinformatics analysis of human adenovirus type 37: New insights into corneal tropism
Christopher M Robinson, Fatemeh Shariati, Allison F Gillaspy, David W Dyer, James Chodosh
BMC Genomics 2008, 9:213 (9May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]






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