The neuronally expressed transcription factor gene ewg is shown to be a major target of the RNA-binding protein ELAV. EWG restricts synaptic growth at neuromuscular junctionsby integrating multiple signal pathways.

The metabolism of C. elegans can be assessed in real time by the constitutive expression of firefly luciferase, which reports in vivo levels of ATP.

Transcript profiling identified an estrogen-responsive target for the mammary oncogene c-Myc, HSPC111, which is overexpressed in breast cancer cells and is associated with adverse patient outcome.

A comprehensive review of the seven main research areas by 56 experts has identified the key gaps and priorities for the greatest potential impact on breast cancer patients.

Detailed analysis of NFB regulons in 1,265 genes differentially expressed in head and neck cancer cell lines differing in p53 status revealed a cross talk between NFkB and specific signaling pathways.