Respiratory Gateway

Novel cell culture protocol mimicking lung physiological conditions promotes human embryonic stem cells to differentiate into major lung epithelium cell lineages.

One in four Mexicans aged 65-69 and nearly half those over 85 are so frail, as measured by a new index created from self-reported deficits, that they have an increased risk of dying in the next two years.

A computer algorithm which inputs clinical parameters provided by ambulance staff can assess a patient's life threat risk at the moment of the emergency call with moderate accuracy and may help improve emergency responses.

Oral administration of geranylgeranylacetone, an anti-ulcer drug that induces heat shock protein 70, exerts a protective effect against lung injury in a drug-induced lung fibrosis mouse model by suppressing the fibrotic reaction.

A genome-wide deletion mutant analysis in budding yeast reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis.

Professor Chris McManus
University College London, UK