Respiratory Gateway

Welcome to BioMed Central's Respiratory Gateway, highlighting the latest articles we have published in this field. Content is continually updated, so please bookmark this page and ensure you check it regularly.

Articles

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    Quantifying benefits and harms

    Randomized trials are not always the best way to ascertain the benefit of medical interventions; Milo Puhan and colleagues argue that quantitative benefit-herm assessments should be used to guide further research, discussing rofilumast as an example. 

    BMC Medicine 2015, 13:157
  • Image attributed to: Lower airways_fromiStockPhoto

    The airway microbiome and respiratory disease

    Benjamin Marsland and Olawale Salami discuss how advances in understanding the airway microbiome and its link to disease is changing the respiratory disease field and generating new leads for therapy.

    Genome Medicine 2015, 7:62
  • Image attributed to: istock photo

    Anti-PCSK9 antibodies improve lipid ratios

    In a systematic review and meta-analysis, anti-PCSK9 antibodies reduce LDL cholesterol, increase HDL cholesterol, and are well-tolerated, suggesting that these drugs have a beneficial effect on lipid profiles and could reduce cardiovascular risk.

    BMC Medicine 2015, 13:123
  • Image attributed to: Image credit: Flickr

    Branching out in lung development

    The tumour suppressor APC plays a critical role in cancer growth, largely through its negative regulation of the Wnt pathway. Shi and colleagues investigate the role of APC in mesenchymal cells in the developing lung, and find surprising results in both the breadth and downstream effects of APC’s dysregulation.

    BMC Biology 2015, 13:42
  • Cancer therapy response

    A single-cell transcriptomic analysis of lung adenocarcinoma patient derived xenografts reveals heterogeneity in the response to anti-cancer drugs

    Genome Biology 2015, 16:127

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News and events

Abstracts from the Severe Asthma Forum

Take a look at the abstracts from EAACI's International Severe Asthma Forum, which have been published in Clinical and Translational Allergy.

Leading open access respiratory journal

Respiratory Research, Edited by Jan Lötvall, Göteborg University and Reynold A Panettieri Jr, University of Pennsylvania is the leading open access journal in the field of respiratory medicine. Covering both clinical and basic research, this journal is essential for any clinician, researcher or other professionals in the field.

Key updates on IPF guidelines and therapeutics

A supplement published in Respiratory Research presents the outcomes of the 2011 AIR: Advancing Idiopathic Pulmonary Fibrosis Research symposium. Edited by Professor Ulrich Costabel, the supplement includes 7 reviews on some of the latest treatment options and guidelines. Read more.

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Editor profile

Jan Lötvall

Göteborg University, Sweden

Hot topics

Allergy

Research

Resistance of infection by Plasmodium vivax to chloroquine in Bolivia

Añez A, Moscoso M, Laguna Á, Garnica C, Melgar V, Cuba M, Gutierrez S and Ascaso C

Malaria Journal 2015, 14:261

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Asthma

Research

Development and content validity testing of a patient-reported outcomes questionnaire for the assessment of hereditary angioedema in observational studies

Bonner N, Abetz-Webb L, Renault L, Caballero T, Longhurst H, Maurer M, Christiansen S, Zuraw B et al.

Health and Quality of Life Outcomes 2015, 13:92

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COPD

Research article

Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study

Theron G, Peter J, Zijenah L, Chanda D, Mangu C, Clowes P, Rachow A, Lesosky M et al.

BMC Infectious Diseases 2015, 15:253

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Lung cancer

Research

Gastrectomy in comprehensive treatment of advanced gastric cancer with synchronous liver metastasis: a prospectively comparative study

Li Z, Fan B, Shan F, Tang L, Bu Z, Wu A, Zhang L, Wu X et al.

World Journal of Surgical Oncology 2015, 13:212

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