Outbreak Prevention & Control Gateway

Welcome to the Outbreak Prevention and Control Gateway. This gateway highlights the latest articles on outbreak prevention and control that is published by BioMed Central journals.


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  • Image attributed to: HIV cartoon

    HIV-1 treatment by RNAi

    John Rossi and colleages review the use of RNA interference against HIV-1 in the clinic, following the development of a number of viral and host targets as well as strategies to overcome immunogenicity, toxicity and viral mutagenesis.

    Genome Medicine 2015, 7:50
  • Image attributed to: Wikimedia by Nephron

    Liver stellate cells as novel target for cancer treatment 

    A comprehensive review summarizes the known molecular interactions between liver stellate cells and liver cancer tumors, as well as novel cancer therapeutic strategies which target liver stellate cells.

    BMC Gastroenterology 2015, 15:63
  • Structure of adenovirus 4 fibre head

    The high-resolution structure of the bovine adenovirus 4 fibre head was described, which is the first solved fibre head structure of an atadenovirus infecting a mammalian host.

    Virology Journal 2015, 12:81
  • Image attributed to: Flickr; J.K. Califf

    Tackling gestational diabetes needs cultural insight

    In an interview-based study, South Asian mothers with gestational diabetes report conflicting advice from peers vs clinicians, and admit socio-cultural factors play a key role, so any behavioral interventions should take into account cultural factors.

    BMC Medicine 2015, 13:120
  • Unfolded protein response in HIV-infected cells

    HIV infection and antiretroviral therapy were found to activate unfolded protein response in host cells, raising the possibility of using this pathway as a drug target in antiviral therapies. 

    Virology Journal 2015, 12:77
  • Image attributed to: wikimedia commons - GrahamColm

    Astroviruses associated with diarrhea in Africa

    Astroviruses were present in 9.9% of 949 stool samples in Africa, with strain MLB1 associated with diarrhea in Kenya, providing new knowledge on astroviruses circulating in that area.

    Virology Journal 2015, 12:78
  • Image attributed to: Flickr; Global Panorma

    Ebola:improving response to epidemics

    The recent Ebola outbreak led to over 10,000 deaths in West Africa; Oyewale Tomori highlights reasons behind the failed control systems, and how improved disease surveillance, capacity building and coordinated response, are vital to the control of future epidemics.

    BMC Medicine 2015, 13:116
  • Image attributed to: istock photo

    Exposure affects malaria susceptibility

    In a low transmission intensity setting, children with multiple episodes of malaria have higher levels of parasite exposure than malaria-free children, but antibody levels are similar, suggesting exposure rather than immunity affects malaria susceptibility.

    BMC Medicine 2015, 13:114
  • Image attributed to: wikimedia commons-Lohrie

    Ginseng vaccine for bovine viral diarrhea

    Transgenic ginseng was used to produce the viral protein Erns, which stimulated immune responses against the virus, providing a new approach to generate the bovine viral diarrhea vaccine.

    Virology Journal 2015, 12:73
  • Goose genome sequence

    The first genome sequence of the goose reveals a mechanism for the susceptibility of geese to fatty liver disease

    Genome Biology 2015, 16:89
  • Follow-up study raises questions over PCV2-free status of a Danish pig herd

    The authors monitored a Danish finishing herd that appeared to be PCV2-free, over two years. They found that the herd was not PCV2-free during the entire period, suggesting that PCV2 vaccination did not eradicate the virus from the herd.

    Porcine Health Management 2015, 1:5
  • Image attributed to: Chikungunya virus - cc A2-33 (Wikipedia)

    Chikungunya virus spreads to Brazil

    In an analysis of epidemiological and clinical data, recent outbreaks of Chikungunya virus in Brazil are caused by imported strains, suggesting surveillance and vector mitigation measures are required to avoid uncontrolled transmission in America.

    BMC Medicine 2015, 13:102
  • Novel method for rapid detection of H7N9

    A multiplex assay for simultaneous detection of H7N9 and influenza A viruses was developed, enabling the laboratory surveillance and rapid diagnosis of these viruses in the future.

    Virology Journal 2015, 12:69
  • Image attributed to: istock

    Universal health and the SDGs

    Viroj Tangcharoensathien and colleagues discuss the forthcoming Sustainable Development Goals (SDGs), highlighting the importance of incorporating universal health coverage within these goals in order to accelerate health equity.

    BMC Medicine 2015, 13:101

News and events

Just published in BMC Public Health: Learning from large scale prevention efforts: findings from Avahan

Launched in 2003 with financial backing from the Bill and Melinda Gates Foundation, Avahan is the world's largest HIV prevention programme. This special supplement documents the role of the initiative in the fight against HIV/AIDS in India.

Edited by Lalit Dandona and Eric Benotsch