Microarrays Gateway

Despite a high level of lateral gene transfer, the phylogeny of Burkholderia pseudomallei is resolved by SNPs in orthologous shared regions, enabling a wider gene-based analysis to define two populations, ancestral Australian, and South East Asian, separated by the Wallace Line.

Mice with a knockout in the PKCI/HINT1 gene display anxiolytic, anti-depressant like and goal-oriented behaviors, that in conjunction with elevated corticosterone levels, suggest a role for this gene in mood regulation.

A web-accessible database of genes that are expressed in the CNS midline lineage during Drosophila embryogenesis integrates expression data with the ability to identify individual cell types and will facilitate studies of neuronal and glial development.

Signal Transducer and Activator of Transcription 1 (STAT1) regulates energy metabolic pathways in tumors, predominantly via glycolytic genes, suggesting a role for STAT1 as a transcriptional modulator of genes involved in "Warburg effect" cancer cell energy production.

The knockdown of 78 transcription factors in differentiating human THP-1 cells using matrix RNAi reveals their interdependence