Medical Imaging Gateway

Updated guidelines for brain injury

The Scandinavian Neurotrauma Committee presents an evidence and consensus-based update of guidelines for the initial management of minimal, mild and moderate head injuries in adults, but highlight that the recommendations also need to be validated in non-Scandinavaian clinical settings.

Is increased use of CPTA justified?

Computed tomography pulmonary angiography (CTPA) to investigate alternative pulmonary diagnoses in patients with suspected pulmonary embolus have a low incidence of identifying an alternative pathology, suggesting that increased use of CPTA is not justified.

Early diagnosis of MCI

Higher levels of amyloid-β deposition, measured using 18F-florbetaben imaging, was associated with more severe memory loss in mild cognitive impairment (MCI) patients, proving its utility in early MCI diagnosis.

mTOR signaling interactions in live cells

Direct interaction of rapamycin (mTOR) with both Ras homologue enriched in brain (RheB) and regulatory associate protein of mTOR (raptor) identified in living cells using Fluorescence resonance energy transfer–fluorescence lifetime imaging (FRET-FLIM).  

Ultrasonography useful in early arthritis diagnosis

Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.