Correlation of antinuclear antibody and anti-double-stranded DNA antibody with clinical response to infliximab in patients with rheumatoid arthritis: a retrospective clinical study

The antinuclear antibodies (ANA) titer before starting treatment may predict clinical response to infliximab, while increased ANA titers or development of anti-ds-DNA antibodies after infliximab treatment may be useful markers of no response.

Adsorption characteristics of an enteric virus-binding protein to norovirus, rotavirus and poliovirus

A broad spectrum virus-binding protein derived from the bacterial chaperon protein GroEL and able to bind rotavirus, norovirus and poliovirus, could be used to detect diverse enteric viruses simultaneously in water and fecal samples.

Effects of abiotic stress on plants: a systems biology perspective

Grant Cramer and colleagues review the role of systems biology in the study of plant responses to abiotic stresses and discuss the future directions for research in this area.

Efficacy and safety of inhaled formoterol 4.5 and 9 μg twice daily in Japanese and European COPD patients: Phase III study results

Inhaled formoterol, a long-lasting beta2-agonist, is well tolerated in patients with chronic obstructive pulmonary disease and significantly increases lung function whilst reducing the need for patients to use reliever medication.

Dynamic lactate indices as predictors of outcome in critically ill patients

Measuring the magnitude, duration and trend of changes in blood lactate concentration over time may be more useful in predicting outcome in critically ill patients than a single measurement taken on admission.