Gastroenterology Gateway

Preventing NSAID induced injuries

Irsogladine provides better protection against NSAID-induced small-intestinal injuries than the PPI Omeprazole in healthy subjects assessed by biochemical approaches and capsule endoscopy, suggesting it could provide protection against NSAID-induced injuries to the entire digestive tract

Depression linked to C.difficile infection

The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.

Autoantibodies increased in celiac disease

Autoantibodies against thrombogenic factors are present at higher levels in children with celiac disease compared with healthy controls, suggesting these antibodies could be a therapeutic target for thrombophilia in celiac patients.

TB risk increased with autoimmunity

An analysis of hospital admissions and death certificates across England reveals the risk of tuberculosis (TB) is significantly increased in patients with immune-mediated diseases, highlighting the need for TB screening in these patients.

Predicting acute liver failure outcomes

The classic MELD score is the best predictor of non-spontaneous recovery from acute liver failure, but the inclusion of serum sodium into the score does not improve its prognostic value