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BMC Research highlights

PMC Biophysics 2009, 2:5
In this study, the stabilities of all core domain missense mutations are predicted and are used to infer their likely inactivation mechanisms. Our correlation analysis shows that loss of protein-protein contacts may be an alternative cause for p53 inactivation.

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BMC Biology 2009, 7:35
Promoter occupancy profiles for the related tumour suppressor proteins p53 and p73 identify many promoters bound by both but also a distinct set bound by p73 in response to genotoxic stress.

BMC Medicine 2009, 7:31
Invasive breast cancer rates have declined dramatically in the US, particularly in urban, affluent counties compared to their less well-off counterparts, potentially reflecting concurrent reductions in the use of hormone therapy.

Wikipedia Lee BMC Med Genomics 1:52
BMC Medical Genomics 2009, 2:37
Activation of growth factor (GF) signalling contributes to the tamoxifen-insensitive estrogen receptor-positive breast cancer phenotype independent of human epidermal growth factor receptor (HER2) gene expression, suggesting an alternative therapeutic target for this aggressive disease.

BMC Medical Research Methodology 2009, 9:42
In order to improve early diagnosis and management of diseases such as ovarian cancer it is imperative that all pertinent information relating to referral, investigation and diagnosis is recorded in electronic patient records.

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Professor Ricardo Saban
Professor Ricardo Saban
Health Services Center, University of Oklahoma, USA


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BMC Latest research articles

Research
Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer
Alberto Alvarado-Miranda, Oscar Arrieta, Carlos Gamboa-Vignolle, David Saavedra-Perez, Rafael Morales-Barrera, Enrique Bargallo-Rocha, Juan Zinser-Sierra, Victor Perez-Sanchez, Teresa Ramirez-Ugalde, Fernando Lara-Medina
Radiation Oncology 2009, 4:24 (11July2009)
[Abstract] [Provisional PDF]

Research article
The potential biomarkers in predicting pathologic response of breast cancer to three different chemotherapy regimens
Linbo Wang, Zhinong Jiang, Meihua Sui, Jianguo Shen, Chaoyang Xu, Weimin Fan
BMC Cancer 2009, 9:226 (11July2009)
[Abstract] [Provisional PDF]

Research
Negligible or weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data from randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)
Susan Li Er Loong, Jacqueline Siok Gek Hwang, Hui Hua Li, Joseph Tien Seng Wee, Swee Peng Yap, Melvin Lee Kiang Chua, Kam Weng Fong, Terence Wee Kiat Tan
Radiation Oncology 2009, 4:23 (10July2009)
[Abstract] [Provisional PDF]

Research
Implications of a high-definition multileaf collimator (HD-MLC) on treatment planning techniques for stereotactic body radiation therapy (SBRT): a planning study
James A Tanyi, Paige A Summers, Charles L McCracken, Yiyi Chen, Li-Chung Ku, Martin Fuss
Radiation Oncology 2009, 4:22 (10July2009)
[Abstract] [Provisional PDF]

Research
Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study
Kazuma Toda, Hitoshi Shibuya, Keiji Hayashi, Fumio Ayukawa
Radiation Oncology 2009, 4:21 (10July2009)
[Abstract] [Provisional PDF]

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