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BMC Research highlights

PMC Biophysics 2009, 2:5
In this study, the stabilities of all core domain missense mutations are predicted and are used to infer their likely inactivation mechanisms. Our correlation analysis shows that loss of protein-protein contacts may be an alternative cause for p53 inactivation.

BMC Medicine 2009, 7:31
Invasive breast cancer rates have declined dramatically in the US, particularly in urban, affluent counties compared to their less well-off counterparts, potentially reflecting concurrent reductions in the use of hormone therapy.

Wikipedia Lee BMC Med Genomics 1:52
BMC Medical Genomics 2009, 2:37
Activation of growth factor (GF) signalling contributes to the tamoxifen-insensitive estrogen receptor-positive breast cancer phenotype independent of human epidermal growth factor receptor (HER2) gene expression, suggesting an alternative therapeutic target for this aggressive disease.

BMC Medical Research Methodology 2009, 9:42
In order to improve early diagnosis and management of diseases such as ovarian cancer it is imperative that all pertinent information relating to referral, investigation and diagnosis is recorded in electronic patient records.

Arthritis Research & Therapy 2009, 11:R95
A small clinical trial has shown masitinib to be generally well tolerated and effective in the treatment of rheumatoid arthritis, indicating the need for further placebo-controlled studies.

BMC New on Faculty of 1000 Biology
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BMC New on Faculty of 1000 Medicine
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BMC Featured video interview

Professor Ricardo Saban
Professor Ricardo Saban
Health Services Center, University of Oklahoma, USA


BMC Latest research articles

Research article
Improved breast cancer survival following introduction of an organized mammography screening program among both screened and unscreened women: a population-based cohort study
Mette Kalager, Tor Haldorsen, Michael Bretthauer, Geir Hoff, Steinar O Thoresen, Hans-Olov Adami
Breast Cancer Research 2009, 11:R44 (3July2009)
[Abstract] [Provisional PDF]

Research article
Dynamics of different sized solid state nanocrystals as tracers for a drug delivery system in the interstitium of a human tumor xenograft
Masaaki Kawai, Hideo Higuchi, Motohiro Takeda, Yoshio Kobayashi, Noriaki Ohuchi
Breast Cancer Research 2009, 11:R43 (3July2009)
[Abstract] [Provisional PDF]

Research
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers
Chun Hei Antonio Cheung, Huang-Hui Chen, Ching-Chuan Kuo, Chi-Yen Chang, Mohane S Coumar, Hsing-Pang Hsieh, Jang-Yang Chang
Molecular Cancer 2009, 8:43 (3July2009)
[Abstract] [Provisional PDF]

Case report
Papillary fibroelastoma of the left atrial wall: a case report
Murat Bicer, Mustafa Cikirikcioglu, Erman Pektok, Hajo Muller, Sarah Dettwiler, Afksendiyos Kalangos
Journal of Cardiothoracic Surgery 2009, 4:28 (1July2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Response of the primary tumor in symptomatic and asymptomatic stage IV colorectal cancer to combined interventional endoscopy and palliative chemotherapy
Silke Cameron, Diana Huenerbein, Tuemen Mansuroglu, Thomas Armbrust, Jens-Gerd Scharf, Harald Schwoerer, Laszlo Fuezesi, Giuliano Ramadori
BMC Cancer 2009, 9:218 (1July2009)
[Abstract] [Provisional PDF]






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