Welcome to BioMed Central's Cancer Gateway, highlighting the latest articles we have published in this field. Content is continually updated, so please bookmark this page and ensure you check it regularly.
Commenting on a recent paper in Cancer and Metabolism, Matthew vander Heiden and colleagues consider the mechanisms by which the anti-diabetic drug metformin can act via mitochondria to combat cancer.
Navdeep Chandel explains in an interview why it has been difficult to establish whether the anti-diabetic drug metformin affects tumor growth, and how the properties of individual tumors may be crucial.
David Gius and colleagues review the evidence that sirtiuns are tumor suppressor proteins that regulate mitochondrial metabolism, thereby linking aging mechanisms with carcinogenesis
As the latest addition to our series of Open Questions, Steven Wiley focuses on the feedback controls on cell signaling and proliferation, and the need to understand how they are disrupted in cancer cells.
Evidence suggests that gene-environment interactions could modify breast cancer risk; Olivia Fletcher and Frank Dudbridge discuss progress in elucidating these interactions, highlighting that further validation in large cohort studies is required.
Authors of BioMed Central cancer-related articles, by location
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