Based on presentations at a workshop held in Santa Barbara, on 7-8 September 2006, this supplement is a collection of research articles related to novel algorithms and enabling techniques for bio- and biomedical image analysis, mining, visualisation, and biology applications

Several genes implicated in food digestion have been deleted or inactivated in platypus. This loss perhaps explains the anatomical and physiological differences in the gastrointestinal tract between monotremes and other vertebrates and provides insights into platypus genome evolution.

Analysis of gene expression in male elderly and young human wounds suggests that estrogen has a more profound influence on aging than previously thought.

A systematic analysis of CpG islands in ten mammalian genomes suggests that an increase in chromosome number elevates GC content and prevents loss of CpG islands.

A 10X draft sequence of Podospora anserina genome shows highly dynamic evolution since its divergence from Neurospora crassa.

The evolutionary distance between human and macaque is particularly attractive for investigating neutral substitution rates, which were calculated as a function of a number of genomic parameters.

Dr Jonathan Steven Alexander
Louisiana State University, Health Services Center

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