Bioinformatics and Genomics Gateway
Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.
Pomaglumetad methionil, a potential new glutamatergic based antipsychotic drug, has a low association with side effects such as weight gain and extrapyramidal symptoms, although evidence for treatment efficacy is low.
Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
Phosphodiesterase (PDE) 4-targeted therapies are a promising option to treat a range of autoimmune diseases; Alice Gottlieb and colleagues review the development of PDE4 inhibitors for chronic conditions and discuss recent clinical trial data.
A label-free integrative pharmacology on-target (iPOT) approach systematically surveys a library of opioid ligands against the opioid receptor family and effectively sorts them into distinct clusters based on their binding and functional selectivity.
According to a meta-analysis, treatment with statins, a drug commonly prescribed to patients at risk of cardiovascular disease, can reduce testosterone levels in both men and women, although the cause for this needs to be determined by further studies.
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Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.
Radiation Oncology 2013, 8:125
Biotechnology for Biofuels 2013, 6:78
BMC Neurology 2013, 13:45