Bioinformatics and Genomics Gateway

Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.

Articles

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  • Image attributed to: Flickr, e-MagineArt.com

    Polypharmacy prevalence increasing

    The occurrence of polypharmacy and adverse drug-drug interactions increased substantially between 1995 and 2010, highlighting the growing complexity of drug regimens and the need for prescribing optimization in those with multiple chronic conditions.

    BMC Medicine 2015, 13:74
  • Cancer therapy response

    An analysis of lung cancer cell lines gene expression in response to drug treatment reveals differential response on the single-cell level

    Genome Biology 2015, 16:66
  • Prognostic perturbation signature

    Denoising perturbation signatures reveals an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine treated ER+ breast cancer

    Genome Biology 2015, 16:61
  • NAHR identification

    New method for the identification of non-allelic homologous recombination from the low coverage sequencing data

    Genome Biology 2015, 16:72
  • Image attributed to: http://www.biomedcentral.com/2046-1682/8/6/abstract

    New label to monitor nucleic acid movement

    A rigid spin label that covalently attaches to the backbone of nucleic acid provides a nucleotide-free way of labeling DNA/RNA and investigating their folding and dynamics.

    BMC Biophysics 2015, 8:6

News and events

Human Genomics has now launched and is accepting submissions

Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.

Submit your manuscript online, and receive updates on this innovative journal's activities and publications by signing up for alerts.

Hot topics

Cancer biomarkers

Research article

snoRNAs are a novel class of biologically relevant Myc targets

Herter EK, Stauch M, Gallant M, Wolf E, Raabe T and Gallant P

BMC Biology 2015, 13:25

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Metagenomics

Research

Probabilistic topic modeling for the analysis and classification of genomic sequences

La Rosa M, Fiannaca A, Rizzo R and Urso A

BMC Bioinformatics 2015, 16(Suppl 6):S2

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Clinical proteomics

Research article

Chlorpromazine-induced perturbations of bile acids and free fatty acids in cholestatic liver injury prevented by the Chinese herbal compound Yin-Chen-Hao-Tang

Yang Q, Yang F, Tang X, Ding L, Xu Y, Xiong Y, Wang Z and Yang L

BMC Complementary and Alternative Medicine 2015, 15:122

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