Bioinformatics and Genomics Gateway

Edinburgh, UK. 28 November 2008.

Novel software utilizing cloud computing technology to cost-effectively align and map SNPs from a human genome in three hours.

COMIT is presented; an algorithm for detecting functional non-coding motifs in coding regions, separating nucleotide and amino acid effects.

Examination of ancestry-informative genetic markers shows that Puerto Rican and Mexican populations have shown strong assortative mating that continues to this day.

Phylogenetically conserved expression patterns in spermatogenesis and testis-specific genes of the male rainbow trout are shown by transcriptome analysis, identifying new pathways involved during spermatogonia self-renewal, meiosis and gamete differentiation.

Heregulin and EGF bind the same receptor and induce similar early responses in breast cancer cells, but a later sequence of transcription factors induced only by heregulin, including FosL1 and FHL2, suppresses ERK signaling to give differentiation rather than proliferation

Dr Jonathan Steven Alexander
Louisiana State University, Health Services Center

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