Bioinformatics and Genomics Gateway

Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.

Articles

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  • Image attributed to: Flickr folder cc RambergMediaimages

    Statins reduce testosterone levels

    According to a meta-analysis, treatment with statins, a drug commonly prescribed to patients at risk of cardiovascular disease, can reduce testosterone levels in both men and women, although the cause for this needs to be determined by further studies.

    BMC Medicine 2013, 11:57
  • Image attributed to: istock

    Effective combined diabetes therapy

    In a 102 week trial, addition of dapagliflozin to metformin therapy for type 2 diabetes patients was effective for glycemic control in those who are inadequately controlled by metformin alone, suggesting a novel therapeutic option for those requiring long-term management.

    BMC Medicine 2013, 11:43
  • Image attributed to: Wikimedia Commons by National Human Genome Research Institute

    Nematode model of early exposure to genotoxicants

    Exposure of developing Caenorhabditis elegans to ultraviolet C radiation results in decreased ATP levels and oxygen consumption in later life, suggesting that early life contact with mitochondrial genotoxicants may lead to time-delayed mitochondrial dysfunction.

    BMC Pharmacology and Toxicology 2013, 14:9
  • Gout therapy: indomethacin more effective than rilonacept

    Treatment with indomethacin alone in patients with acute gout flare is more effective than treatment with rilonacept and no greater pain relief is provided when used in combination with rilonacept. 

    Arthritis Research & Therapy 2013, 15:R25
  • Image attributed to: Adverse reaction to penicllin from wikimedia commons

    Pharmacogenomics of adverse drug reactions

    Ann Daly reviews progress in identification of pharmacogenomic risk factors for serious adverse drug reactions, including different approaches used, and prospects for further progress.

    Genome Medicine 2013, 5:5

News and events

Human Genomics has now launched and is accepting submissions

Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.

Submit your manuscript online, and receive updates on this innovative journal's activities and publications by signing up for alerts.

Hot topics

Cancer biomarkers

Review

Cancer stem cell contribution to glioblastoma invasiveness

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Ortensi B, Setti M, Osti D and Pelicci G

Stem Cell Research & Therapy 2013, 4:18

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Metagenomics

Research article

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

Murri M, Leiva I, Gomez-Zumaquero JM, Cardona F, Soriguer F, Tinahones FJ and Queipo-Ortuno MI

BMC Medicine 2013, 11:46

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Clinical proteomics

Review

Functional decorations: post-translational modifications and heart disease delineated by targeted proteomics

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Liddy KA, White MY and Cordwell SJ

Genome Medicine 2013, 5:20

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