Bioinformatics and Genomics Gateway
Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.
Computational analysis of proteins that interact with alpha-helical peptides suggests no sequence requirements for binding and highlights the presence of hydrophobic regions at the protein surface and non-uniform hydrophobicity across binding pockets.
Administration of an intravenous alfentanil bolus before CT colonography significantly reduces pain during colonic insufflation compared to administration of a placebo and could improve acceptance of CT colonography for colorectal cancer screening
Pomaglumetad methionil, a potential new glutamatergic based antipsychotic drug, has a low association with side effects such as weight gain and extrapyramidal symptoms, although evidence for treatment efficacy is low.
Rats treated with CNX-011-67 demonstrate improved glucose mediated insulin secretion and insulin gene transcription, enhanced glucose oxidation in the form of increased islet ATP content and overall improvement in beta cell health.
Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
News from around the web
- 19 June 2013
- A shot in the arm for old antibiotics
News and events
Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.
BMC Bioinformatics 2013, 14:198
BMC Genomics 2013, 14:390
BMC Veterinary Research 2013, 9:116