Based on presentations at a workshop held in Santa Barbara, on 7-8 September 2006, this supplement is a collection of research articles related to novel algorithms and enabling techniques for bio- and biomedical image analysis, mining, visualisation, and biology applications

A 10X draft sequence of Podospora anserina genome shows highly dynamic evolution since its divergence from Neurospora crassa.

The evolutionary distance between human and macaque is particularly attractive for investigating neutral substitution rates, which were calculated as a function of a number of genomic parameters.

Increased stromal collagen density in mouse mammary tissue increases both tumor formation and tumor cell invasive and migratory properties by three fold; furthermore, a metabolic signature for flavin adenine dinucleotide is identified in invading metastatic cells.

Comparative genome hybridization in 38 widely used laboratory strains of the social amoeba Dictyostelium discoideum detects previously unreported duplications and deletions in the Dictyostelium genome and highlights genetic variability between strains.

PubMed abstracts can now be effectively screened for articles related to human genetic association studies and genome epidemiology using GAPscreener, a free java-based tool.

Dr Jonathan Steven Alexander
Louisiana State University, Health Services Center

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