Bioinformatics and Genomics Gateway

Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.

Articles

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Transformation for translational toxicology

The integration of exposure assessment, basic toxicology and models to investigate effective interventions that mitigate or reverse adverse effects of environmental exposures may represent an effective portfolio to improve health by minimizing exposure and producing specific therapeutics.

BMC Pharmacology and Toxicology 2013, 14:51
Nebivolol-stimulated nitric oxide and peroxynitrite release

The ability of nebivolol to stimulate nitric oxide release appears to be independent of its selective beta1-adrenoceptor blockade properties and dependent on stimulation of beta3-adrenoceptors and ATP-mediated stimulation of P2Y-purinergic receptors in human endothelial cells.

BMC Pharmacology and Toxicology 2013, 14:48
Hallmarks of acetaminophen-induced liver injury

Serum proteomic profiling in healthy subjects reveals that increased levels of several acute phase and other immune proteins are present in those who develop signs of acetaminophen-induced liver injury.

Genome Medicine 2013, 5:86
What can cancer mutation signatures tell us?

Reuben Harris discusses how mutational signatures could be diagnostic, prognostic, and therapeutic biomarkers, highlighting a recent study that found several signatures across different cancer types.

Genome Medicine 2013, 5:87
PAR-CLIP of snoRNAs

PAR-CLIP of snoRNA-associated proteins reveals the existence of extensive human loci that are processed into snoRNAs

Genome Biology 2013, 14:R45

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News from around the web

02 October 2013: Gene expression databases could uncover therapeutic targets, biological processes

02 October 2013: Scientist sniffs out possible new tick species

01 October 2013: Genes associated with unhealthy liver function

News and events

Human Genomics has now launched and is accepting submissions

Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.

Submit your manuscript online, and receive updates on this innovative journal's activities and publications by signing up for alerts.