Bioinformatics and Genomics Gateway

Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.

Articles

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  • Circular RNAs

    An analysis of ENCODE data reveals circular mRNAs and casts doubt on the theory that they might act as miRNA sponges

    Genome Biology 2014, 15:409
  • One year’s microbiome

    Changes in the saliva and gut microbiome of two individuals over the course of a year

    Genome Biology 2014, 15:R89
  • Image attributed to: iStock

    Metabolites linked to pregnancy outcome

    Urinary metabolites collected in early pregnancy are associated with increased risk of preterm birth and fetal growth restriction, indicating that metabolic profiling could be used to predict those at risk of adverse pregnancy outcome.

    BMC Medicine 2014, 12:110
  • Bias in RNA-seq

    A new approach, in vitro transcription sequencing, reveals RNA-seq coverage biases introduced by library preparation protocols

    Genome Biology 2014, 15:R86
  • Image attributed to: Fig 2 from Anjum et al.

    Predicting breast cancer

    A blood-based DNA methylation signature derived from BRCA1 carriers is able to predict non-hereditary breast cancer risk and death years in advance of diagnosis.

    Genome Medicine 2014, 6:47

News and events

Human Genomics has now launched and is accepting submissions

Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.

Submit your manuscript online, and receive updates on this innovative journal's activities and publications by signing up for alerts.

Hot topics

Cancer biomarkers

Research

Pleomorphic adenoma gene 1 mediates the role of Karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma

Hu Z, Yuan S, Yang Y, Zhou W and Jiang H

Journal of Experimental & Clinical Cancer Research 2014, 33:61

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Metagenomics

Research

The dynamics of a family’s gut microbiota reveal variations on a theme

Schloss PD, Iverson KD, Petrosino JF and Schloss SJ

Microbiome 2014, 2:25

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Clinical proteomics

Research article

A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype

Cheng Q, Chang JT, Gwin WR, Zhu J, Ambs S, Geradts J and Lyerly HK

Breast Cancer Research 2014, 16:407

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