RNAi Gateway

Welcome to the BioMed Central RNAi gateway, highlighting the latest BioMed Central articles, interesting news, and relevant external sites offering insight into the application of RNAi pathways in experimental biology.

Articles

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HIV/AIDS

How has the era of genomics advanced our understanding of HIV/AIDS epidemiology and pathogenesis?

Genome Biology 2013, 14:201
Reviewing radiosensitizers in prostate cancer

Charles Rosser et al. review the efficacy of radiation therapy in prostate cancer and discuss the intrinsic microenvironment of tumours and how radiosensitizing agents may be used to improve the efficacy of radiation therapy.

BMC Urology 2013, 13:4
Balancing lipid and protein synthesis in cancer

Akt/mTORC1 signalling via SREBP was shown to coordinate lipid and protein biosynthesis in both normal and cancer cells, while ablation of this pathway caused ER stress, apoptosis and cell death and prevented tumor growth in a mouse model.

Cancer & Metabolism 2013, 1:3
Vinculin not the way in for Staphylococcus aureus

Complementation of vinculin in vinculin-deficient cells, shRNA-mediated knock-down and overexpression in different cell types suggests that vinculin may be insignificant for integrin-mediated internalization of Staphylococcus aureus.

BMC Cell Biology 2013, 14:2
ADAR RNA editors

ADARs and RNA editing: a Protein Family Review by Robert Reenan and colleagues

Genome Biology 2012, 13:252

RNA: Methods and Protocols

A new thematic series, now accepting submissions

Silence is inviting submissions for a new article series on methods and protocols in analyzing RNA.

This special collection of articles will provide novel insights into the latest methods within the field of RNA, addressing questions of general interest to the RNA community, as well as predictions on future uses, modifications and improvements that would advance existing methods beyond their current use.

To submit your manuscript, please use our online submission system and indicate in your covering letter that you would like it to be considered for the series, or alternatively, send a pre-submission enquiry to editorial@silencejournal.com.