MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7

MicroRNA let-7a binds directly to the 3'UTR of C-C chemokine receptor type 7 (CCR7), blocking its protein expression and suppressing migration and invasion of breast cancer cells.

Reversal of type 1 diabetes via islet beta cell regeneration following immune modulation by cord blood-derived multipotent stem cells

The safe reversal of Type 1 diabetes is possible with Stem Cell Educator therapy which uses stem cells from cord blood to re-educate a diabetic's own T cells, restarts pancreatic function, and reduces the need for insulin.

Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine

Jonghwan Kim and Stuart Orkin review recent genome-scale and systems approaches to understand the regulatory networks that are common to embryonic stem (ES) cells and cancer.

Heat shock factor binding in Alu repeats expands its involvement in stress through an antisense mechanism

HSF binding to conserved sites in Alu repeats initiates an antisense transcript-mediated response to heat shock

A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits

The discovery of many new Caenorhabditis species reveals the independent evolution of hermaphroditism in several of these nematode species and allows their natural habitat, rotten fruits and flowers, to be defined for the first time.