The antiproliferative effects of vitamin D on a breast tumour cell line persist despite knockdown of the vitamin D receptor gene, and variants resistant to these anti-proliferative effects do not show changes in known vitamin D signaling pathway genes.

A loss-of-function ras allele (rasKP) causes excessive apoptosis in the Drosophila eye via activation of JNK and, to a lesser extent, Hid, with cell and organ size also affected in the wing.

Our understanding of how SAPS-related proteins differentially regulate closely-related Ser/Thr phosphatases is advanced by a study indicating that human PP6R3 forms distinctive helical repeats within its conserved SAPS domain and uses interhelical loops to associate with protein phosphatase 6.

Treating lymphoblastic cell lines derived from schizophrenia patients with glucose deprivation and combining exon array, mRNA and genotyping analysis identifies stress related exon-specific expression changes and SNP variants potentially linked to this psychological disorder.

Many previously uncharacterized genes uncovered by a subtractive hybridization analysis of early Drosophila development are spatiotemporally regulated during embryogenesis, including genes encoding a set of secreted and transmembrane proteins.