- Nitin Baliga, Institute for Systems Biology
- Christina Chan, Michigan State University
- Luonan Chen, Chinese Academy of Sciences
- Sang Yup Lee, Korea Advanced Institute of Science and Technology
- Pedro Mendes, Univ. of Manchester/Univ. Connecticut Health Center
- Matteo Pellegrini, University of California, Los Angeles
- Tim Sands, BioMed Central
A new flux balance analysis method predicts internal cell fluxes of growth below optimal rates based on the optimization of protein cost at sub-optimal biomass objective levels, and simulations predict features of E.coli central carbon metabolism.
Across ammonite genera, trade-offs between different shape phenotypes resulted in a small range of successful forms, that could be represented by a pyramid in the diagram of possible shape parameters, with each point representing an optimized archetype.
The use of inhibitors to components of cancer signaling pathways is dogged by resistance and cross-talk upregulating compensatory pathways. A new computational framework characterizes the cross-talks between pathways in breast cancer cell lines.
BMC Systems Biology 2015, 9:21
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BMC Systems Biology is an open access, peer-reviewed journal that considers articles on experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level, in particular those addressing the engineering of biological systems, network modeling, quantitative analyses and the integration of different levels of information.
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Volume 9 Suppl 2 (15 April 2015)
Selected articles from the IX International Conference on the Bioinformatics of Genome Regulation and Structure\Systems Biology (BGRS\SB-2014): Systems Biology
Novosibirsk, Russia. 23-28 June 2014
Volume 9 Suppl 1 (21 January 2015)
Selected articles from the Thirteenth Asia Pacific Bioinformatics Conference (APBC 2015): Systems Biology
HsinChu, Taiwan. 21-23 January 2015
Volume 8 Suppl 5 (12 December 2014)
Proceedings of the 25th International Conference on Genome Informatics (GIW/ISCB-Asia): Systems Biology
Tokyo, Japan. 15-17 December 2014