Section Editors

  • Nitin Baliga, Institute for Systems Biology
  • Christina Chan, Michigan State University
  • Luonan Chen, Chinese Academy of Sciences
  • Sang Yup Lee, Korea Advanced Institute of Science and Technology
  • Pedro Mendes, Univ. of Manchester/Univ. Connecticut Health Center
  • Matteo Pellegrini, University of California, Los Angeles

Executive Editor

  • Tim Sands, BioMed Central


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  • Image attributed to: GeeJo on Wikipedia, CC BY-SA 2.0

    Reduction of genome scale models

    The size and complexity of genome-scale metabolic models means that analysis may be computationally impractical and stoichiometric methods unusable, but a new algorithm, NetworkReducer, extracts a meaningful core network to facilitate analysis.

    BMC Systems Biology 2015, 9:48
  • Image attributed to: User KGH on Wikipedia, CC BY-SA 3.0

    Inferring urothelial cancer GRNs

    Genome-wide regulatory networks underling urothelial cancer, inferred by the BC3Net algorithm based on RNAseq, Bead and Oligo gene expression data, identified known associated genomic regions, and found similarity between functional subnetworks but gene interactions were highly dataset specific.

    BMC Systems Biology 2015, 9:21


BMC Systems Biology is an open access, peer-reviewed journal that considers articles on experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level, in particular those addressing the engineering of biological systems, network modeling, quantitative analyses and the integration of different levels of information.

BMC Systems Biology is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.

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Latest supplements

Volume 9 Suppl 4 (11 June 2015)

Selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM) 2014: Systems Biology

San Antonio, TX, USA. 4-6 December 2014

Volume 9 Suppl 3 (1 June 2015)

Proceedings of the Italian Society of Bioinformatics (BITS): Annual Meeting 2014: Systems Biology

Rome, Italy. 26-28 February 2014

View all supplements

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ISSN: 1752-0509