Section Editors

  • Nitin Baliga, Institute for Systems Biology
  • Christina Chan, Michigan State University
  • Luonan Chen, Chinese Academy of Sciences
  • Sang Yup Lee, Korea Advanced Institute of Science and Technology
  • Pedro Mendes, Univ. of Manchester/Univ. Connecticut Health Center
  • Matteo Pellegrini, University of California, Los Angeles

Executive Editor

  • Tim Sands, BioMed Central

Articles

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  • New approach to computing elementary flux modes

    A new algorithm to calculate elementary flux modes in genome-scale, gives similar speed to existing Double Description approaches but is scalable, and can incorporate additional flux constraints to generate a full subset of EFMs of interest.

    BMC Systems Biology 2014, 8:94
  • Sponge interaction network in breast cancer

    A new computation approach to the role of long non-coding RNAs to act as competing endogenous RNAs (miRNA “sponges”) finds that there is a marked rewiring between normal and cancerous breast tissue.

    BMC Systems Biology 2014, 8:83
  • Image attributed to: Fig. 2c

    A novel Gene regulatory network reverse-engineering method

    A new gene regulatory network inference method based on polynomial dynamical systems incorporates time-resolved gene expression data and  existing causal information and into its model inference and uses and evolutionary algorithm for parameter estimation

    BMC Systems Biology 2014, 8:37

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Scope

BMC Systems Biology is an open access, peer-reviewed journal that considers articles on experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level, in particular those addressing the engineering of biological systems, network modeling, quantitative analyses and the integration of different levels of information.

BMC Systems Biology is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.

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ISSN: 1752-0509