- Nitin Baliga, Institute for Systems Biology
- Christina Chan, Michigan State University
- Luonan Chen, Chinese Academy of Sciences
- Sang Yup Lee, Korea Advanced Institute of Science and Technology
- Pedro Mendes, Univ. of Manchester/Univ. Connecticut Health Center
- Matteo Pellegrini, University of California, Los Angeles
- Tim Sands, BioMed Central
Genome-wide regulatory networks underling urothelial cancer, inferred by the BC3Net algorithm based on RNAseq, Bead and Oligo gene expression data, identified known associated genomic regions, and found similarity between functional subnetworks but gene interactions were highly dataset specific.
A new flux balance analysis method predicts internal cell fluxes of growth below optimal rates based on the optimization of protein cost at sub-optimal biomass objective levels, and simulations predict features of E.coli central carbon metabolism.
Across ammonite genera, trade-offs between different shape phenotypes resulted in a small range of successful forms, that could be represented by a pyramid in the diagram of possible shape parameters, with each point representing an optimized archetype.
The use of inhibitors to components of cancer signaling pathways is dogged by resistance and cross-talk upregulating compensatory pathways. A new computational framework characterizes the cross-talks between pathways in breast cancer cell lines.
BMC Systems Biology 2015, 9:30
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Volume 9 Suppl 4 (11 June 2015)
Selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM) 2014: Systems Biology
San Antonio, TX, USA. 4-6 December 2014
Volume 9 Suppl 3 (1 June 2015)
Rome, Italy. 26-28 February 2014
Volume 9 Suppl 2 (15 April 2015)
Selected articles from the IX International Conference on the Bioinformatics of Genome Regulation and Structure\Systems Biology (BGRS\SB-2014): Systems Biology
Novosibirsk, Russia. 23-28 June 2014