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  • Image attributed to:

    ß-clamp structure from an extremophile

    The crystal structure of the DNA polymerase III beta subunit from Deinococcus radiodurans sheds light on the mechanisms of efficient DNA metabolism that enable this bacterium to survive high doses of radiation.

    BMC Structural Biology 2015, 15:5
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    Leishmania enzyme structure

    The crystal structure of nucleoside diphosphate kinase from the parasite L. braziliensis provides reveals a partially unfolded C-terminus that could serve as a potential target for drug therapies.

    BMC Structural Biology 2015, 15:2
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    Chromatin modification and lysine context

    Molecular modeling of the recognition and modification of histones by the oncogenic NSD class of histone methyl transferases sheds light on the dynamics of these interactions, potentially aiding the design of inhibitors for chemotherapies.

    BMC Structural Biology 2014, 14:25
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    Antibiotic resistance in E. coli

    The structure of polymyxin B resistance protein D from E. coli reveals distinct features differing from those of closely related species that may help determine its mechanisms of antibiotic resistance.

    BMC Structural Biology 2014, 14:24
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    Bacterial pyruvate decarboxylase structure

    The Gluconacetobacter diazotrophicus enzyme responsible for breaking down pyruvate into acetaldehyde and carbon dioxide, an important intermediate step in the production of ethanol, is structurally similar to pyruvate decarboxylases from other bacterial species.

    BMC Structural Biology 2014, 14:21
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