- James Chou, Harvard Medical School
- Jianping Ding, Shanghai Institutes of Biological Sciences
- Jean-Luc Pellequer, CEA Marcoule
- Paul A Ramsland, Macfarlane Burnet Institute for Medical Research and Public Health
- Torsten Schwede, Biozentrum Univ. of Basel, SIB Swiss Institute of Bioinformatics
- Simon Harold, BioMed Central
The intrinsic dynamics of human beta2-adrenergic receptor are dramatically altered when intracellular loop 3 is included in molecular dynamic and elastic network models, indicated a strong coupling between extracellular and intracellular parts of the intact receptor.
The first crystal structures of Malyl-CoA lyase (MCL), an enzyme that plays a crucial role in autotrophic CO2 fixation, reveals divergent primary structures between two different phylogenetic subgroups, although tertiary and quaternary structures remain similar.
gEMpicker is a highly parallel correlation-based particle picking tool for high-throughput analysis that will allow experimentalists to rapidly achieve higher resolution 3D reconstructions from cryo-electron micrograph images.
Protein structures determined under via the Protein Structure Initiative: Biology (PSI:Biology) have a higher rate of annotations than structures determined during the first two phases of PSI, as well as those determined exclusive of these partnerships.
Crystallisation of signal regulatory protein SIRPgamma complexed with the Fab fragment of the OX117 antibody reveals conservation of binding domains between members of the SIRP family and dimerization specific to the crystal structure.
BMC Structural Biology 2013, 13:29
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Volume 13 Suppl 1 (8 November 2013)
Philadelphia, PA, USA. 4 October 2012
Section Editor's profile
Dr Ramsland is currently the Sir Zelman Cowen Fellow and a Group Leader in the Centre for Immunology at the Burnet Institute (Melbourne, Australia). His research examines the diverse structural roles of carbohydrates and glycoproteins in immunity and infection (Structural Glycobiology) using crystallography, computational modelling, automated docking and solution scattering techniques. He has over 90 scientific publications including primary research papers, reviews/chapters and has recently co-edited a book on Structural Glycobiology.
"Together with Dr Cy Jeffries, Deputy Section Editor, I am pleased to be involved in guiding the development of the Small-Angle Scattering section of BMC Structural Biology. This new section incorporates all aspects of the structural analysis of biological macromolecules using techniques in small-angle scattering including but not limited to: studies incorporating substantial analysis by small-angle X-ray scattering and/or neutron scattering."