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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Danielle Talbot


Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure and function of biological macromolecules. BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Scientific (ISI) and Google Scholar.



BMC Featured articles

Credit: authors fig 1
BMC Structural Biology 2008, 8:5
Prediction of functional sites in protein structures by Dynamic Perturbation Analysis is markedly quicker and done with comparable accuracy when entropy is estimated rather than measured directly, which is ideal for web servers and high-throughput analyzes.


BMC  Latest articles published in BMC Structural Biology        [more info]


Research article
Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
Zhen Xu, Ekta Kohli, Karl I Devlin, Michael Bold, Jay C Nix, Saurav Misra
BMC Structural Biology 2008, 8:26 (16May2008)
[Abstract] [Provisional PDF]

Software
K2D2: estimation of protein secondary structure from circular dichroism spectra
Carolina Perez-Iratxeta, Miguel A Andrade-Navarro
BMC Structural Biology 2008, 8:25 (13May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Improving the accuracy of template-based predictions by mixing and matching between initial models
Tianyun Liu, Michal Guerquin, Ram Samudrala
BMC Structural Biology 2008, 8:24 (5May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Exploring Allosteric Coupling in the alpha-Subunit of Heterotrimeric G Proteins Using Evolutionary and Ensemble-Based Approaches
Kemal Sayar, Ozlem Ugur, Tong Liu, Vincent J Hilser, Ongun Onaran
BMC Structural Biology 2008, 8:23 (2May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: Towards the design of higher-affinity inhibitors
Corinne Hazan, Franois Boudsocq, Virginie Gervais, Olivier Saurel, Marion Ciais, Christophe Cazaux, Jerzy Czaplicki, Alain Milon
BMC Structural Biology 2008, 8:22 (16April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Software
PSAIA Protein Structure and Interaction Analyzer
Josip Mihel, Mile iki, Sanja Tomi, Branko Jeren, Kristian Vlahoviek
BMC Structural Biology 2008, 8:21 (9April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog
Matthew J Cuneo, Yaji Tian, Malin Allert, Homme W Hellinga
BMC Structural Biology 2008, 8:20 (28March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Charge environments around phosphorylation sites in proteins
James Kitchen, Rebecca E Saunders, Jim Warwicker
BMC Structural Biology 2008, 8:19 (25March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
A multi-template combination algorithm for protein comparative modeling
Jianlin Cheng
BMC Structural Biology 2008, 8:18 (17March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Solution structure of the Legionella pneumophila Mip-rapamycin complex
Andreas Ceymann, Martin Horstmann, Philipp Ehses, Kristian Schweimer, Anne-Katrin Paschke, Michael Steinert, Cornelius Faber
BMC Structural Biology 2008, 8:17 (17March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Andrew J Bordner, Andrey A Gorin
BMC Bioinformatics 2008, 9:234 (12May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells
Estela Sasso-Cerri, Paulo S Cerri
Reproductive Biology and Endocrinology 2008, 6:18 (9May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Software
CPSP-tools - exact and complete algorithms for high-throughput 3D lattice protein studies
Martin Mann, Sebastian Will, Rolf Backofen
BMC Bioinformatics 2008, 9:230 (7May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Lukasz Kurgan, Krzysztof Cios, Ke Chen
BMC Bioinformatics 2008, 9:226 (1May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
PCR-based gene synthesis to produce recombinant proteins for crystallization
Damien Marsic, Ronny C Hughes, Miranda L Byrne-Steele, Joseph D Ng
BMC Biotechnology 2008, 8:44 (29April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
ConStruct: improved construction of RNA consensus structures
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
BMC Bioinformatics 2008, 9:219 (28April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Method
Evolutionary potentials: structure specific knowledge-based potentials exploiting the evolutionary record of sequence homologs
Alejandro Panjkovich, Francisco Melo, Marc A Marti-Renom
Genome Biology 2008, 9:R68 (8April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review
Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry
Bohumila Suchanova, Roman Tuma
Microbial Cell Factories 2008, 7:12 (4April2008)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Methodology article
RNACompress: Grammar-based compression and informational complexity measurement of RNA secondary structure
Qi Liu, Yu Yang, Chun Chen, Jiajun Bu, Yin Zhang, Xiuzi Ye
BMC Bioinformatics 2008, 9:176 (31March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The pyrroloquinoline quinone biosynthesis pathway revisited: A structural approach
Sandra Puehringer, Moritz Metlitzky, Robert Schwarzenbacher
BMC Biochemistry 2008, 9:8 (27March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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