Articles
Volume 2 (2009) - June 2009
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Research article
Structural and functional implications of p53 missense cancer mutations Yuhong Tan, Ray Luo PMC Biophysics 2009, 2:5 (26 June 2009) In this study, the stabilities of all core domain missense mutations are predicted and are used to infer their likely inactivation mechanisms. Our correlation analysis shows that loss of protein-protein contacts may be an alternative cause for p53 inactivation.
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