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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Biochemistry published by BioMed Central
BMC Biochemistry is an open access journal publishing original peer-reviewed research articles in all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.
BMC Biochemistry (ISSN 1471-2091) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Biochemistry 2009, 10 :24
Our understanding of how SAPS-related proteins differentially regulate closely-related Ser/Thr phosphatases is advanced by a study indicating that human PP6R3 forms distinctive helical repeats within its conserved SAPS domain and uses interhelical loops to associate with protein phosphatase 6.
BMC Biochemistry 2009, 10 :23
Cathepsin cysteine proteases are active under conditions simulating extracellular and intracellular compartments with a range of pHs and redox potentials, as shown by cleavage of the natural substrate thyroglobulin in distinct ways in different physiologic environments.
BMC Biochemistry 2009, 10 :17
Two response regulators of antibacterial peptide production in Lactobacillus plantarum are highly homologous, co-expressed, and bind to the same promoters but differ in their binding affinity and cooperativity, explaining their opposite functions in gene regulation.
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Research article
Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate Christina Ramel, Micha Tobler, Martin Meyer, Laurent Bigler, Marc-Olivier Ebert, Barbara Schellenberg, Robert Dudler BMC Biochemistry 2009, 10 :26 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ser170 of Bacillus thuringiensis Cry1Ab Manduca sexta brush border membranes Oscar Alzate, Craig F Hemann, Cristina Osorio, Russ Hille, Donald H Dean BMC Biochemistry 2009, 10 :25 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Mapping of protein phosphatase-6 association with its SAPS domain regulatory subunit using a model of helical repeats Julien Guergnon, Urszula Derewenda, Jessica R Edelson, David L Brautigan BMC Biochemistry 2009, 10 :24 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions Silvia Jordans, Sa BMC Biochemistry 2009, 10 :23 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of a nuclear localization motif in the serine/arginine protein kinase PSRPK of physarum polycephalum Shide Liu, Zhuolong Zhou, Ziyang Lin, Qiuling Ouyang, Jianhua Zhang, Shengli Tian, Miao Xing BMC Biochemistry 2009, 10 :22 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Contribution of oenocytes and pheromones to courtship behaviour in Drosophila Claude Wicker-Thomas, Ilhem Guenachi, Youssouf F Keita BMC Biochemistry 2009, 10 :21 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Biochemical characterization of malate synthase G of P. aeruginosa Bart Roucourt, Nikki Minnebo, Patrick Augustijns, Kirsten Hertveldt, Guido Volckaert, Rob Lavigne BMC Biochemistry 2009, 10 :20 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity Po-Wen Chang, Amrita Madabushi, A-Lien Lu BMC Biochemistry 2009, 10 :19 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol Thirunavukkarasu Annamalai, Neil Dani, Bokun Cheng, Yuk-Ching Tse-Dinh BMC Biochemistry 2009, 10 :18 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11 Daniel Straume, Rune F Johansen, Magnar Bj BMC Biochemistry 2009, 10 :17 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Elucidation of functional consequences of signalling pathway interactions Adaoha E C Ihekwaba, Phuong T Nguyen, Corrado Priami BMC Bioinformatics 2009, 10 :370 (6 [Abstract ] [Provisional PDF ]
Research article
Cbl-Associated Protein is tyrosine phosphorylated by c-Abl and c-Src kinases Inga Fernow, Ana Tomasovic, Ann Siehoff-Icking, Ritva Tikkanen BMC Cell Biology 2009, 10 :80 (5 [Abstract ] [Provisional PDF ]
Research
Lack of association between mutations of gene encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan Jin-Bor Chen, Tsu-Kung Lin, Shang-Chih Liao, Wen-Chin Lee, Lung-Chih Lee, Chia-Wei Liou, Pei-Wen Wang, Mao-Meng Tiao Journal of Negative Results in BioMedicine 2009, 8 :10 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Enrichment and proteomic analysis of plasma membrane from rat dorsal root ganglions Xia Xiong, Sha Huang, Hai Zhang, Jianjun Li, Jianying Shen, Yong Lin, Jixian Xiong, Liping Jiang, Xianchun Wang, Songping Liang Proteome Science 2009, 7 :41 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus Louise A Russo, Bryan J Peano, Shreya P Trivedi, Todd D Cavalcanto, Benjamin A Olenchock, Joseph A Caruso, Amanda R Smolock, Oleg Vishnevsky, Russell M Gardner Reproductive Biology and Endocrinology 2009, 7 :124 (4 [Abstract ] [Provisional PDF ]
Research
Bovine viral diarrhea virus NS4B protein is an integral membrane protein associated with Golgi markers and rearranged host membranes Erica Weiskircher, Jason Aligo, Gang Ning, Kouacou V Konan Virology Journal 2009, 6 :185 (3 [Abstract ] [Provisional PDF ]
Short report
TRIM5alpha and TRIMCyp form apparent hexamers and their multimeric state is not affected by exposure to restriction-sensitive viruses or by treatment with pharmacological inhibitors Marie-Edith Nepveu-Traversy, Julie Berube, Lionel Berthoux Retrovirology 2009, 6 :100 (3 [Abstract ] [Provisional PDF ]
Research article
Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia Georgios T Karapanagiotidis, Polychronis Antonitsis, Nicholas Charokopos, Christophoros N Foroulis, Kyriakos Anastasiadis, Efthymia Rouska, Helena Argiriadou, Kyriakos Rammos, Christos Papakonstantinou Journal of Cardiothoracic Surgery 2009, 4 :59 (3 [Abstract ] [Provisional PDF ]
Research article
Functional characterization of two CITED3 homologs (gcCITED3a and gcCITED3b) in the hypoxia-tolerant grass carp, Ctenopharyngodon idella Patrick KS Ng, Sung-Kay Chiu, Theresa FN Kwong, Richard MK Yu, Minnie ML Wong, Richard YC Kong BMC Molecular Biology 2009, 10 :101 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators Hyun-Mi Choi, Yeon-Ah Lee, Sang-Hoon Lee, Seung-Jae Hong, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim Arthritis Research & Therapy 2009, 11 :R161 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
-endotoxin becomes anchored in a hydrophobic moiety upon insertion of this protein into Manduca sexta brush border membranes
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