Maximal endothelial NO concentration, ATP release, and [NO]/[ONOO-] ratio stimulated with nebivolol. Maximal NO (A) and ATP (B) concentration release from HUVECs stimulated with different concentrations of nebivolol, along with the [NO]/[ONOO-] ratio (C). Values are mean ± SD (n = 5). One-way ANOVA, Student-Newman-Keuls multiple comparison post-hoc test: *P < 0.05 compared with basal (in the absence of nebivolol) (A, B) and 0.1 μM nebivolol (C).
Mason et al. BMC Pharmacology and Toxicology 2013 14:48 doi:10.1186/2050-6511-14-48