Figure 3.

Maximal endothelial NO and ONOO- concentrations, and [NO]/[ONOO-] ratio stimulated with nebivolol, L-755,507, 2-MeSATP, and ATP. (A) Maximal NO and ONOO- concentration release from HUVECs stimulated with nebivolol, L-755,507, 2-MeSATP, and ATP (each at 1 μM). Values are mean ± SD (n = 5). One-way ANOVA, Student-Newman-Keuls multiple comparison post-hoc test: *P < 0.05 compared with either the maximal NO or ONOO- concentration released by cells stimulated with nebivolol. (B) The [NO]/[ONOO-] ratio calculated from the maximal concentration in A. Values are mean ± SD (n = 5). One-way ANOVA, Student-Newman-Keuls multiple comparison post-hoc test: *P < 0.05 compared with [NO]/[ONOO-] ratio calculated for nebivolol.

Mason et al. BMC Pharmacology and Toxicology 2013 14:48   doi:10.1186/2050-6511-14-48
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