Table 3

Geometrical and physicochemical characteristics of the identified pockets
Protein code PDB Volume (Å3) Hydrophobicity score Local hydrophobic density
Chicken calmodulin 312.0 68.86 43.00
2O5G
Human calmodulin 203.0 68.86 42.00
1ZUZ
Human calmodulin 219.8 59.62 40.00
2VAY
Human calmodulin 226.4 61.00 39.32
3DVE
E.coli calmodulin 317.9 56.63 40.15
1QTX
Rat calmodulin 310.6 56.62 43.78
2HQW
Human centrin 2 147.9 41.47 32.00
2GGM
Human centrin 2 210.9 39.93 35.08
2K2I
Scherffelia dubia centrin 221.5 58.19 31.00
3KF9
Human BCL-XL 321.5 36.91 42.04
1BXL
Human E3 ubiquitin-protein ligase MDM2 201.9 51.18 55.20
1YCR
Rabbit cardiac troponin C 213.1 63.07 39.15
1A2X

Isvoran et al.

Isvoran et al. BMC Pharmacology and Toxicology 2013 14:31   doi:10.1186/2050-6511-14-31

Open Data