Figure 4.

Inhibition of cellular IKKβ mediated NF-κB activity. HepG2 cells stably transfected with the NF-κB–luciferase gene were stimulated with TNF-α pre-incubated with the indicated concentrations of 1 and other three hit compounds (compounds 3, 9 and 10). Cell lysates were analyzed for luciferase activity to determine the extent of NF-κB inhibition. Error bars represent the standard deviations of the results from three independent experiments.

Leung et al. BMC Pharmacology and Toxicology 2013 14:3   doi:10.1186/2050-6511-14-3
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