Figure 9.

Dose responses of a panel of opioid ligands in HEK-KOR cells. (a) Dose dependent responses of opioid ligands obtained using DMR agonist assays. The maximal amplitudes were plotted as a function of agonist doses. Data represents the mean ± s.d. for 2 independent measurements, each in duplicate (n = 4). (b) Dose-dependent inhibition of the DMR of 64 nM BRL-57532 by opioid ligands. The maximal amplitudes of the BRL-57532 DMR were plotted as a function of ligand doses. Data represents the mean ± s.d. for 2 independent measurements, each in duplicate (n = 4).

Morse et al. BMC Pharmacology and Toxicology 2013 14:17   doi:10.1186/2050-6511-14-17
Download authors' original image