ALT activity in the silkworm hemolymph injected with various hepatotoxic drugs. Silkworms fasted 6 h were injected with ferric sulfate, sodium valproate, tetracycline, or amiodarone hydrochloride (A), and with methyldopa, ketoconazole, or pemoline (B), and 1 d later the silkworm hemolymph was collected to measure ALT activity. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. negative control. (n = 5).
Inagaki et al. BMC Pharmacology and Toxicology 2012 13:13 doi:10.1186/2050-6511-13-13