Single-molecule photobleaching of MET receptor. (A) Fluorescence intensity trajectories found for InlB-ATTO647N in uninduced HeLa cells. In most cases, one-step photobleaching was observed. The histograms on the right show the distribution of fluorescence intensities. (B) InlB induced cells show an increase in two-step photobleaching of fluorescence spots, reporting on MET dimers.
Dietz et al. BMC Biophysics 2013 6:6 doi:10.1186/2046-1682-6-6