FA intensity is lower in fast migrating cells and FA number per cell is slightly higher in fast migrating cells. Histograms of FA intensity A.-B. and FA number per cell D.-E. were generated by dividing cells into two cell migration speed groups (A., D. slow (<42 μm/hr) and B., E. fast (>42 μm/hr)). Histograms were fit with lognormal probability distributions. The mean values of FA C. intensity and F. number per cell are also shown. The number of measurements of FA number per cell is the product of the average number of frames and the cell number. The number of measurements of FA properties is the product of the average FA number and the cell number. Intensity: Ncell,slow = 21, NFA,slow = 12,773, Ncell,fast = 34, NFA,fast = 16,862. Number per cell: Ncell,slow = 21, NFA,slow = 6146, Ncell,fast = 34, NFA,fast = 10,245. Error bars are 95 % confidence intervals and asterisks denote p < 0.01.
Hou et al. BMC Biophysics 2012 5:8 doi:10.1186/2046-1682-5-8