Open Access Highly Accessed Research article

Stochastic dynamics of virus capsid formation: direct versus hierarchical self-assembly

Johanna E Baschek1, Heinrich C R Klein1 and Ulrich S Schwarz12*

Author Affiliations

1 Institute for Theoretical Physics, University of Heidelberg, Heidelberg, Germany

2 BioQuant, University of Heidelberg, Heidelberg, Germany

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BMC Biophysics 2012, 5:22  doi:10.1186/2046-1682-5-22

Published: 17 December 2012

Additional files

Additional file 1:

Movie showing direct assembly. Representative movie showing the direct assembly of a T1 capsid from 60 monomers. As no switching in bond reactivity occurs, all particles are shown as dark blue spheres with white reactive patches. Snapshots are shown in Figure 1 (top).

Format: AVI Size: 17.8MB Download file

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Additional file 2:

Movie showing hierarchical assembly. Representative movie showing the hierarchical assembly of a T1 capsid from 60 monomers. Here the color switch from light blue to red for the intermediate clusters indicates the transition in reactivity upon completed formation of a pentamer ring. Snapshots are shown in Figure 1 (bottom).

Format: AVI Size: 15.8MB Download file

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Open Data