Comparison with previously-determined structure. (a) Superimposition of 11 present structures (red) with previously-determined 3 structures (blue; 3KH and 2WO1) of the EphA4 LBD in the closed form. (b) Superimposition of 5 present structures (green) with previously-determined 6 structures (3KH, 3GXU, 2WO2, 2WH3 and ref. ) of the EphA4 LBD in the open form. The open structures in the uncomplexed state are colored in red while the open structures complexed with ephrin are in blue.
Qin et al. BMC Biophysics 2012 5:2 doi:10.1186/2046-1682-5-2