Background source and sink activities do not significantly perturb the R ∼ P gradient even for high rates.A) Schematic of localization of source and sink activities; the green and red shading represent the background activity. B) Mathematical modeling of the effects of background source and sink activities on the distributions of [R ∼ P]. (Inset) The ratio of [R ∼ P] between the two poles is not significantly affected by background source and sink rates.
Tropini et al. BMC Biophysics 2012 5:17 doi:10.1186/2046-1682-5-17