Resolution:
## Figure 3.
Source and sink saturation does not significantly reduce the R ∼ P gradient except
in very stringent saturation conditions.A) Schematic of localization of source and sink. B) Mathematical modeling of the R ∼ P concentration near the phosphatase pole [R ∼ P]_{phos}normalized to the total response regulator concentration [R_{tot}] for varying σ_{p}, and σ_{k} = 10 and 100/s. C) The effective phosphatase rate σ_{p,e}is high enough to outcompete diffusion except when the number of enzymes is less than
10% than of the substrate.
Tropini |