Resolution:
## Figure 2.
Localized degradation does not significantly affect to the R ∼ P gradient even at
high proteolysis rates.A) Schematic of the localization of source and sink. Synthesis occurs throughout the
cell, whereas degradation occurs only at the phosphatase pole. B) Mathematical modeling of the effects of proteolysis on the distributions of R ∼ P
for α = 1/τ_{D}. (Left inset) The total amount of substrate is not uniform. (Right inset) The ratio
of R ∼ P between the two poles is independent of the synthesis rate.
Tropini |