The block diagram for the transient activity. The environmental temperature, Input1, passes through three blocks to regulate the transient activity. The cascade connection implies that the output signal from one block equals the input signal for the next block. The time intervals on which Input1 is different from 37°C are adjacent to each other (no recovery time).
Cates et al. BMC Biophysics 2011 4:16 doi:10.1186/2046-1682-4-16