Photomicrographs showing FISH painted human chromosome 1 (red) and 2 (green) in metaphase after exposure to 60Co γ-rays. (a) Un-irradiated control cell showing two normal red chromosomes and two green chromosomes. (b) Chromosome 1 showing break. (c) Broken part of chromosome 2 (1 inset), translocation between chromosome 1 and 2 (2 inset) as well as chromosome 1 and unpainted chromosome (3 inset). (d) Reciprocal translocation between chromosome 2 and an un-painted chromosome (1 inset). (e) Both chromosomes 1 and 2 are involved in reciprocal translocation with un-painted chromosomes.
Pathak et al. BMC Medical Physics 2009 9:6 doi:10.1186/1756-6649-9-6