Table 5

RECIST, WHO and volume analyses from US, CT and MR images of UTHSCSA multimodality tumor measurement phantom

Design

Image RECIST and WHO (mean ± SD (% error))


US

CT

MRI


RECIST (mm)

37.00

37.05 ± 0.05 (+0.13 ± 0.13%)

37.62 ± 0.12 (+1.69 ± 0.33%)

37.39 ± 0.13 (+1.05 ± 0.34%)

WHO (mm2)

365.00

359.634 ± 0.93 (-1.47 ± 0.25%)

368.76 ± 1.47 (+1.03 ± 0.39%)

359.96 ± 2.09 (-1.38 ± 0.57%)


Image Volume (mean ± SD (% error))


US

CT

MRI


Volume (mm3)

4.19 (2 mm sphere)

3.55 ± 0.00 (-15.34 ± 0.04%)

3.42 ± 0.45 (-18.30 ± 10.65%)

4.43 ± 0.03 (+5.72 ± 0.60%)

33.51 (4 mm sphere)

32.76 ± 0.33 (-2.24 ± 0.99%)

32.56 ± 0.83 (-2.84 ± 2.49%)

34.05 ± 1.24 (+1.62 ± 3.70%)

179.59 (7 mm sphere)

180.71 ± 1.71 (+0.62 ± 0.95%)

179.41 ± 4.06 (-0.10 ± 2.26%)

180.84 ± 4.25 (+0.70 ± 2.36%)

523.60 (10 mm sphere)

520.27 ± 3.19 (-0.64 ± 0.61%)

537.90 ± 4.08 (+2.73 ± 0.78%)

495.65 ± 3.97 (-5.34 ± 0.76%)

1436.76 (14 mm sphere)

1408.59 ± 5.67 (-1.96 ± 0.39%)

1450.39 ± 11.22 (+0.95 ± 0.78%)

1406.47 ± 8.16 (-2.11 ± 0.57%)

Slope [95% CI]

0.980 ± 0.003 [0.969 to 0.991]

1.011 ± 0.004 [0.997 to 1.025]

0.977 ± 0.008 [0.951 to 1.002]

Intercept [95% CI]

2.277 ± 2.261 [-4.919 to 9.472]

0.413 ± 3.052 [-9.299 to 10.12]

-1.013 ± 5.613 [-18.87 to 16.85]

R2

1.000

0.9999

0.9998

p-value

<0.0001

<0.0001

<0.0001


Mean ± standard deviation (SD) for three repeated measures and % errors in parenthesis are shown for RECIST, WHO and volume analyses. The same analysis methods as described for the Mark 1 and Mark 2 phantoms were used. Slope and intercepts [95% confidence intervals], correlation coefficient (R2) and p-value of linear regression lines for volume of test objects also are shown.

Lee et al. BMC Medical Physics 2011 11:1   doi:10.1186/1756-6649-11-1

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