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Open Access Case Report

Compression neuropathy caused by cancer metastasis to the optic nerve canal

Hiroshi Tamai12*, Kazuyuki Ishida3, Kensuke Murakami4, Norio Narita45, Teiji Tominaga4 and Nobuo Fuse26

Author Affiliations

1 Department of Ophthalmology, Kesennuma City Hospital, 184 Tanaka, Kesennuma, Miyagi 988-0052, Japan

2 Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

3 Department of Neurosurgery, Kesennuma City Hospital, 184 Tanaka, Kesennuma, Miyagi 988-0052, Japan

4 Department of Pathology, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

5 Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

6 Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan

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BMC Research Notes 2013, 6:546  doi:10.1186/1756-0500-6-546

Published: 20 December 2013

Abstract

Background

Cancerous cells are known to metastasize to different ocular structures. This happens especially to the choroid in males with lung cancer and females with breast cancer. However, we observed two cases of cancerous metastasis to the optic canal region. Both cases showed only a progressive decrease in vision without any other remarkable ophthalmological symptoms or abnormalities in the affected eye.

Case presentation

Two females, a 60-year-old and a 73-year-old, came to our hospital because of progressive loss of vision. These patients showed no remarkable symptoms or signs in their eyes except visual acuity loss. Several ophthalmoscopic examinations, such as slit lamp microscopy and fundoscopy, showed no abnormal changes in their affected eye but magnetic resonance imaging indicated a massive legion around the optic nerve.

Conclusion

It is possible for cancer to metastasize to the optic canal region and the existence of primary tumors should be considered.

Keywords:
Cancer; Metastasis; Optic canal