Table 2

Identification of functional modules in the AC landscape
Module Correlation cut-off Description of the key GO term GO enrichment P-value
>0.95 >0.90 >0.85 >0.80 >0.70 none
Mitochondria 291 39 512 40 35 35 mitochondrial electron transport, NADH to ubiquinone 2.0370*102E-26
Ribosome 18 37 23 29 33 translation 3.7793*103.8E-47
Muscle 6 10 12 10 10 10 muscle contraction, muscle system process 3.0278*103E-8
Regulation of ubiquitin-protein ligase activity 8 13 11 nd3 negative regulation of ubiquitin-protein ligase activity 1.2510*101.3E-5
Translation 6 nd translational elongation 1.1387*101.1E-8

1 Number of genes in each module for each correlation cut-off of the “AC” landscape was calculated using the MCODE plug-in in Cytoscape. A list of genes in each module is included in Additional file 3.

2 Bold values have been taken as the optimal size of the module.

3 Module not detected.

Sun et al.

Sun et al. BMC Research Notes 2012 5:632   doi:10.1186/1756-0500-5-632

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